P0878

O-Phospho-L-serine

• Synonym(s): L-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate
• Linear Formula: (HO)₂P(O)OCH₂CH(NH₂)CO₂H
• CAS Number: 407-41-0
• Molecular Weight: 185.07
• Beilstein: 1726826
• Número EC: 206-986-0
• Número MDL: MFCD00065935
• eCl@ss: 32160406
• ID de substância PubChem: 24277998
• NACRES: NA.32

Properties

• forma: powder
• Nível de qualidade: 200
• condição de armazenamento: under inert gas
• pf: 190 °C (lit.)
• SMILES string: N[C@@H](COP(O)(O)=O)C(O)=O
• InChI: 1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
• InChI key: BZQFBWGGLXLEPQ-REOHCLBHSA-N
• Gene Information: human ... GRM4(2914) , GRM7(2917) , GRM8(2918)

Description

Aplicação

O-Phospho-L-serine has been used:

• for the expression, purification and phosphorylation of protein
• to study its chemical shift
• to spectroscopically determine its pKa values using Raman spectroscopy

Embalagem

10 mg in autosample vial

1, 5, 25, 100 g

Ações bioquímicas/fisiológicas

O-Phospho-L-serine (L-SOP) is a molecule which resembles phosphatidylserine head group and it mediates partial inhibition of microglial phagocytosis of apoptotic cells. In zebrafish, L-SOP inhibits Müller glia proliferation and blocks cone cell regeneration in the light-damaged retina. In vivo, L-SOP acts as a substrate for CysM, a cysteine synthase from Mycobacterium tuberculosis.

Group III metabotropic glutamate receptor agonist (mGluR₄, mGluR₇, and mGluR₈).

Safety Information

• Pictogramas: GHS05
• Palavra indicadora: Danger
• Frases de perigo: H314
• Declarações de precaução: P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Skin Corr. 1B
• Código de classe de armazenamento: 8B - Non-combustible, corrosive hazardous materials
• WGK: WGK 1
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)