Merck
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P4562

Sigma-Aldrich

Piruvato de sódio

powder, BioXtra, suitable for mouse embryo cell culture

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Sinônimo(s):
αÁcido α-cetopropiônico, Ácido 2-oxopropanoico, Ácido pirúvico
Fórmula linear:
CH3COCOONa
Número CAS:
Peso molecular:
110.04
Beilstein:
3568341
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.75

linha de produto

BioXtra

Nível de qualidade

Ensaio

≥99%

forma

powder

technique(s)

cell culture | embryo: suitable

pf

>300 °C (lit.)

solubilidade

H2O: 100 mg/mL

temperatura de armazenamento

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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1 of 4

Este Item
P8574S8636105477
Sodium pyruvate powder, BioXtra, suitable for mouse embryo cell culture

Sigma-Aldrich

P4562

Sodium pyruvate

-
Sodium pyruvate BioXtra, ≥99%

Sigma-Aldrich

P8574

Sodium pyruvate

Premium Grade
Sodium pyruvate solution 100 mM, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

S8636

Sodium pyruvate solution

-
Sodium pyruvate EMPROVE® ESSENTIAL

SAFC

105477

Sodium pyruvate

-
form

powder

form

powder

form

solution

form

solid

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

-

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL

solubility

H2O: 1 M, clear, colorless

solubility

-

solubility

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

400

Quality Level

500

Descrição geral

Pyruvate, the end-product of the glycolysis pathway, is the anion of pyruvic acid.

Aplicação

Sodium pyruvate has been used:
  • as a supplement in Ca2+ + N-Tris(hydroxymethil)methyl-2-aminoethanesulfonic acid (TES)–NaCl medium for sperm incubation
  • as a supplement in TCM-199 hepes modification solution for cumulus-oocytes complexes (COC′s) culture
  • as a supplement in Dulbecco′s modified Eagle medium (DMEM) to culture mouse primary hepatocytes (MPHs) and also to intraperitoneally inject fasted mice for glucose production assessment

Ações bioquímicas/fisiológicas

Sodium pyruvate is mainly used as a constituent in culture broth and media. It exhibits anti-oxidation and anti-inflammatory properties. Hence sodium pyruvate is considered a possible therapy for allergic rhinitis. Sodium pyruvate might also be a new approach treating lactic acidosis.
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted at 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Eye Irrit. 2 - Skin Sens. 1B

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Exemplo

T1503
Número do produto
-
25G
Tamanho/quantidade da embalagem

Exemplos adicionais:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

inserir como 1.000309185)

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Sodium pyruvate

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Pyruvic acid sodium salt for biochemistry

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Kyle S McCommis et al.
The Biochemical journal, 466(3), 443-454 (2015-03-10)
Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely
L S Li et al.
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 31(2), 103-106 (2017-01-20)
Objective:Pyruvate is a key intermediate in several metabolic pathways of human body Sodium pyruvate possesses anti-oxidation and anti-inflammatory effects, which make it a possible novel therapy for allergic rhinitis. However, the relevant clinical research is rare. The aim of the
In vitro maturation of caprine oocytes in different concentrations of estrous goat serum
Kharche SD, et al.
Small Ruminant Research (2006)
Jing Yang et al.
Artificial cells, nanomedicine, and biotechnology, 44(1), 48-55 (2014-04-05)
To examine the effects of sodium pyruvate (SP) on metabolic acidosis. For the in vivo experiments, we evaluated effects of SP on an ammonium chloride (NH4Cl)-induced hyperchloremic acidosis rat model. SP was infused at overall doses of 2, 4, and
Rangga Setiawan et al.
Animal reproduction science, 233, 106843-106843 (2021-09-15)
Adenosine triphosphate (ATP) production via glycolysis and oxidative phosphorylation is essential for the maintenance of flagellar motility in sperm; however, the primary energy production pathways supporting fertilization vary among species. Inconsistency in thought exists regarding which pathways maintain ATP production

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