P5638

Sigma-Aldrich

L-α-Phosphatidylcholine

from soybean, Type II-S, 14-29% choline basis

Sinônimo(s):
L-α-Lecithin, Azolectin, 3-sn-Phosphatidylcholine, PC, 1,2-Diacyl-sn-glycero-3-phosphocholine
Número CAS:
Beilstein/REAXYS Number:
5209585
Número EC:
NACRES:
NA.25

fonte biológica

soybean

Nível de qualidade

200

tipo

Type II-S

teor

14-29% choline basis

forma

powder or solid

grupo funcional

phospholipid

enviado em

ambient

temperatura de armazenamento

2-8°C

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

Procurando produtos similares? Visit Guia de comparação de produtos

Categorias relacionadas

Descrição geral

P5638 is a crude extract of soybean phospholipids.

Typical lots of purified soybean phosphatidylcholine have fatty acid contents of approximately 13% C16:0 (palmitic), 4% C18:0 (stearic), 10% C18:1(oleic), 64% C18:2 (linoleic), and 6% 18:3 (linolenic) with other fatty acids being minor contributors. This would calculate to an average molecular weight of approximately 776.

Purified phosphatidylcholine is soluble in chloroform and ethanol.

Other major phospholipid components include phosphatidylethanolamine and inositol phosphatides. Other phospholipids and neutral lipids such as triglycerides, tocopherols, and sterols may be present. Carbohydrates may also be present.

A procedure for determination of the amount of oxidation of egg phosphatidylcholine in a liposome preparation by measurement of the oxidation index has been published. The oxidation index is the ratio of the absorbance at 233 nm to the absorbance at 215 nm. The latter wavelength was chosen since there is little contribution of the fatty acid carbonyl to the absorbance at this wavelength, allowing Beer′s Law to be followed.

A method of determining choline content has been published.

Embalagem

500 g in poly bottle
1 kg in poly bottle

Ações bioquímicas/fisiológicas

Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells. In addition to being the major structural component of cellular membranes, phosphatidylcholine serves as a reservoir for several lipid messengers. It is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet activating factor, and arachidonic acid.

Phosphatidylcholine is used for preparation of vesicle suspensions, commonly called liposomes, or as monolayers. Monolayers have been formed using a solution of 1% soybean phosphatidylcholine in hexane.

Valinomycin-induced changes in membrane potentials of red blood cell and phospholipid (phosphatidylcholine from egg yolk plus cholesterol) vesicle suspensions have been measured using positively-charged, cyanine dyes that fluorimetrically responded to the change in potential.

Purified rhodopsin has been incorporated into soybean phosphatidylcholine vesicles.
A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.

Qualidade

P5638 is a crude soy extract that contains many other lipids.

storage_class_code

11 - Combustible Solids

WGK Alemanha

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

R Cassia-Moura et al.
Journal of theoretical biology, 206(2), 235-241 (2000-09-01)
Dynamic activation of ion channels formed by colicin Ia incorporated into a planar bilayer lipid membrane (BLM) was investigated by the voltage clamp technique using different step voltage stimuli. We have demonstrated a critical resting interval, Deltat(c), between two identical...
Ruchika Bajaj et al.
MicrobiologyOpen, 5(5), 738-752 (2016-05-12)
The FtsEX:PcsB complex forms a molecular machine that carries out peptidoglycan (PG) hydrolysis during normal cell division of the major respiratory pathogenic bacterium, Streptococcus pneumoniae (pneumococcus). FtsX is an integral membrane protein and FtsE is a cytoplasmic ATPase that together...
The detection of oxidation in liposome preparations.
R A Klein
Biochimica et biophysica acta, 210(3), 486-489 (1970-09-08)
Liposomes in Gene Delivery
Lasic, D.D. et al.
CRC Press (1997)
Burcu Ustuner et al.
Animal reproduction science, 164, 97-104 (2015-12-20)
The aim of the current study was to evaluate the effects of different concentrations of rainbow trout seminal plasma (RTSP) (0.1%, 1% and 10%) in extenders containing either egg yolk or lecithin for use in Awassi ram semen cryopreservation. Pooled...

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica