Merck
All Photos(4)

P6126

Sigma-Aldrich

(R)-(−)-Phenylephrine hydrochloride

powder

Synonym(s):
(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
Linear Formula:
HOC6H4CH(CH2NHCH3)OH·HCl
CAS Number:
Molecular Weight:
203.67
Beilstein:
4158948
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.77

forma

powder

Nível de qualidade

200

pf

143-145 °C (lit.)

originador

Johnson & Johnson

SMILES string

OC1=CC([C@H](CNC)O)=CC=C1.Cl

InChI

1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key

OCYSGIYOVXAGKQ-FVGYRXGTSA-N

Gene Information

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Descrição geral

(R)-(-)-Phenylephrine hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug.[1]

Aplicação

(R)-(-)-Phenylephrine hydrochloride has been used:
  • in the preparation and culturing of cardiocytes and fibroblasts[2]
  • to stimulate myocardial strips to measure slice contraction[3]
  • in primary cardiomyocyte culture to show the effect of Kruppel-like factors (KLF) on cardiac hypertrophy in vivo[4]
  • to evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytes[5]
  • to pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality[6]

Embalagem

5, 10, 25, 50, 100 g in glass bottle

Ações bioquímicas/fisiológicas

α1-adrenoceptor agonist.

Características e benefícios

This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Skin Sens. 1

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificate of Analysis

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Certificate of Origin

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