Merck
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P9625

Sigma-Aldrich

Phenazine methosulfate

≥90% (UV)

Sinônimo(s):
PMS, N-Methylphenazonium methyl sulfate, 5-Methylphenazinium methyl sulfate
Fórmula linear:
C13H11N2 · CH3SO4
Número CAS:
Peso molecular:
306.34
Beilstein:
3898869
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.77

Nível de qualidade

200

teor

≥90% (UV)

forma

powder

pf

158-160 °C (dec.) (lit.)

λ

0.01 g/L in H2O, 1 cm path

Absorção UV

λ: 387.5 nm Amax: ≥90%

espectro de atividade do antibiótico

fungi

Modo de ação

DNA synthesis | interferes
cell membrane | interferes

temperatura de armazenamento

−20°C

SMILES string

COS([O-])(=O)=O.C[n+]1c2ccccc2nc3ccccc13

InChI

1S/C13H11N2.CH4O4S/c1-15-12-8-4-2-6-10(12)14-11-7-3-5-9-13(11)15;1-5-6(2,3)4/h2-9H,1H3;1H3,(H,2,3,4)/q+1;/p-1

InChI key

RXGJTUSBYWCRBK-UHFFFAOYSA-M

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Descrição geral

Phenazines are heterocyclic compounds produced as secondary metabolites by bacteria.

Aplicação

Phenazine methosulfate is used with ascorbic acid to determine nitric oxide reductase activity.
Phenazine methosulfate has been used:
  • as a component of succinate dehydrogenase enzyme substrate solution
  • to induce superoxide radical generation in red blood cell suspensions and to study its influence on RBC deformability
  • as a component of complex II histochemistry media

Embalagem

500 mg in glass bottle
1, 5, 10, 25 g in glass bottle

Ações bioquímicas/fisiológicas

Phenazine m ethosulfate (PMS) acts as a good electron acceptor. PMS is reduced non-enzymatically by (nicotinamide adenine dinucleotide) NADH and (nicotinamide adenine dinucleotide phosphate) NADPH.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificado de análise

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Certificado de origem

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María Gabriela Villamizar-Sarmiento et al.
Nanomaterials (Basel, Switzerland), 9(7) (2019-07-03)
We report on the design, development, characterization, and a preliminary cellular evaluation of a novel solid material. This material is composed of low-molecular-weight hyaluronic acid (LMWHA) and polyarginine (PArg), which generate aqueous ionic nanocomplexes (INC) that are then freeze-dried to
Duong Luong et al.
Materials science & engineering. C, Materials for biological applications, 103, 109759-109759 (2019-07-28)
Transition metals (TM) are essential microelements with various biological functions demanded in tissue regeneration applications. Little is known about therapeutic potential of TM within soft hydrogel biomaterials. The soluble divalent TM, such as Zn, Cu, Mn and Co, were stably
Richard Y Wu et al.
Microbiome, 5(1), 135-135 (2017-10-12)
Prebiotics are non-digestible food ingredients that enhance the growth of certain microbes within the gut microbiota. Prebiotic consumption generates immune-modulatory effects that are traditionally thought to reflect microbial interactions within the gut. However, recent evidence suggests they may also impart
Assessment of oxidant susceptibility of red blood cells in various species based on cell deformability
Simmonds MJ, et al.
Biorheology, 48(5-6), 293-304 (2011)
Handbook on Clostridia, , pages=, 84-84 (2005)

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