Merck
All Photos(2)

PZ0117

Sigma-Aldrich

PF-573228

≥95% (HPLC)

Synonym(s):
6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one, PF-228
Empirical Formula (Hill Notation):
C22H20F3N5O3S
CAS Number:
Molecular Weight:
491.49
Número MDL:
ID de substância PubChem:
NACRES:
NA.77

Nível de qualidade

100

teor

≥95% (HPLC)

forma

powder

manufacturer/tradename

Pfizer®

cor

white to off-white

solubilidade

DMSO: ≥20 mg/mL

originador

Pfizer

temperatura de armazenamento

2-8°C

SMILES string

CS(=O)(=O)c1cccc(CNc2nc(Nc3ccc4NC(=O)CCc4c3)ncc2C(F)(F)F)c1

InChI

1S/C22H20F3N5O3S/c1-34(32,33)16-4-2-3-13(9-16)11-26-20-17(22(23,24)25)12-27-21(30-20)28-15-6-7-18-14(10-15)5-8-19(31)29-18/h2-4,6-7,9-10,12H,5,8,11H2,1H3,(H,29,31)(H2,26,27,28,30)

InChI key

HESLKTSGTIBHJU-UHFFFAOYSA-N

Related Categories

Embalagem

5, 25 mg in glass bottle

Ações bioquímicas/fisiológicas

PF-573228 is a focal adhesion kinase (FAK) inhibitor; Non-receptor tyrosine kinase inhibitor.

Características e benefícios

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Fak page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Outras notas

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informações legais

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

Código de classe de armazenamento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Certificate of Analysis

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Certificate of Origin

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