R4500

(−)-Riboflavin

from Eremothecium ashbyii, ≥98%

• Synonym(s): Lactoflavin, Vitamin B₂, Vitamin G
• Empirical Formula (Hill Notation): C₁₇H₂₀N₄O₆
• CAS Number: 83-88-5
• Molecular Weight: 376.36
• Beilstein: 97825
• Número EC: 201-507-1
• Número MDL: MFCD00005022
• eCl@ss: 34058005
• ID de substância PubChem: 57654591
• NACRES: NA.79

Properties

• fonte biológica: Eremothecium ashbyii
• Nível de qualidade: 200
• teor: ≥98%
• forma: powder
• cor: yellow to orange
• pf: 290 °C (dec.) (lit.)
• temperatura de armazenamento: room temp
• SMILES string: CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1
• InChI: 1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1
• InChI key: AUNGANRZJHBGPY-SCRDCRAPSA-N

Description

Descrição geral

Riboflavin belongs to the vitamin-B family and contains a pentose side chain ribitol.

Aplicação

Riboflavin has been used:

• to check the role of riboflavin diet in rats
• as a supplement in HECM-6 medium (hamster embryo culture medium)
• as a supplement in the bacterial basal media

Ações bioquímicas/fisiológicas

Riboflavin is a key component of the redox cofactors flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) that are used by a wide variety of flavoprotein oxidoreductases, dehydrogenase(s), decarboxylase(s) and electron transporters. Riboflavin is involved in various cellular processes, including β oxidation in lipid metabolism, glucose metabolism, protection from cellular oxidative injury, DNA and RNA metabolism, gluconeogenesis, erythropoiesis and generation of corticosteroids. Riboflavin deficiency causes ariboflavinosis with symptoms such as sore throat, hyperemia, edema of oral and mucous membranes, cheilosis and glossitis.

Safety Information

• Código de classe de armazenamento: 11 - Combustible Solids
• WGK: WGK 1
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)