Merck
All Photos(2)

S0758

Sigma-Aldrich

Sulfaphenazole

≥98%

Synonym(s):
4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
Empirical Formula (Hill Notation):
C15H14N4O2S
CAS Number:
Molecular Weight:
314.36
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.77

Nível de qualidade

100

teor

≥98%

forma

powder

solubilidade

ethanol: 25 mg/mL, clear, colorless to yellow

temperatura de armazenamento

2-8°C

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ccnn2-c3ccccc3

InChI

1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2

InChI key

QWCJHSGMANYXCW-UHFFFAOYSA-N

Gene Information

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Aplicação

Sulfaphenazole has been used as a positive control to inhibit cytochrome P450 2C9 (cyp2c9) to quantify Rhodiola rosea inhibition.[1] It has also been used as cytochrome P450 2C9 (cyp2c9) inhibitor in endothelial cells[2] and microsomal preparations.[3]

Embalagem

1 g in poly bottle

Ações bioquímicas/fisiológicas

Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release.

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 2

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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