S3386

Sigma-Aldrich

Sorbitan sesquioleate

nonionic surfactant

Sinônimo(s):
Span® 83, Arlacel® 83
Número CAS:
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.25

Nível de qualidade

200

fonte biológica

corn

pressão de vapor

0.81 psi ( 20 °C)

forma

liquid

índice de refração

n20/D 1.478 (lit.)

densidade

0.989 g/mL at 25 °C (lit.)

grupo funcional

ester

enviado em

ambient

temperatura de armazenamento

room temp

SMILES string

OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C2OC[C@H](O)[C@H]2O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/3C18H34O2.2C6H12O5/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;2*7-1-3(8)6-5(10)4(9)2-11-6/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);2*3-10H,1-2H2/b3*10-9-;;/t;;;2*3-,4+,5-,6-/m...11/s1

InChI key

SPFRYHCSFBFNTR-RKGWDQTMSA-N

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Descrição geral

Sorbitan sesquioleate (SSO) is a sorbitol derivative emulsifier. It is a common emulsifier component in topical corticosteroids, topical antibiotics, topical antifungals, moisturizing creams and lotions and topical retinoids.

Embalagem

1 L in glass bottle
250 mL in glass bottle

Ações bioquímicas/fisiológicas

Sorbitan sesquioleate is useful as a stabilizing agent in polymerization process to produce spherical acrylamide beads. It has been used in many topical agents. SSO have recently been implicated in allergic dermatitis.

Outras notas

Fatty acid composition: Oleic acid (C18:1) approx. 70%; balance primarily palmitic acid (C16:0), stearic acid (C18:0) and linoleic acid (C18:2).

Informações legais

Arlacel is a registered trademark of Croda International PLC
Span is a registered trademark of Croda International PLC

storage_class_code

10 - Combustible liquids

WGK Alemanha

WGK 1

Ponto de fulgor (ºF)

235.4 °F - closed cup

Ponto de fulgor (ºC)

113 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificado de análise

Certificado de origem

Contact dermatitis.
Flora B de Waard-van der Spek et al.
Contact dermatitis, 59(1), 67-67 (2008-07-05)
M Iwata et al.
Journal of microencapsulation, 16(1), 49-58 (1999-02-11)
PLGA multiphase microspheres were prepared by the multiple emulsion solvent evaporation method using acetonitrile as the polymer solvent and mineral oil as the evaporation medium. The preparation process was further developed in the present study to reduce the particle size...
E Larmi et al.
Contact dermatitis, 19(5), 368-371 (1988-11-01)
In order to study the effects of an emulsifier on non-immunologic immediate contact reactions, 500, 250, 125, 62, and 31 mM benzoic acid (BA) was tested in 12 medical students on a skin area of the upper back treated with...
Adam Asarch et al.
Dermatitis : contact, atopic, occupational, drug, 19(6), 339-341 (2009-01-13)
Sorbitol-based emulsifiers such as sorbitan sesquioleate (SSO) are commonly used in topical corticosteroids, topical antibiotics, topical antifungals, moisturizing creams and lotions, and topical retinoids. Contact dermatitis from sorbitol derivatives appears to be increasingly prevalent. Patch-testing with SSO can be useful...
Kinetic evaluation of biotransformation of benzaldehyde to L-phenylacetylcarbinol by immobilized pyruvate decarboxylase from Candida utilis
Shin HS and Rogers PL
Biotechnology and Bioengineering, 49(4), 429-436 (1996)

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