Merck
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S7446

Sigma-Aldrich

Superoxide Dismutase from bovine erythrocytes

BioUltra, lyophilized powder, ≥4,500 units/mg protein, ≥97% (SDS-PAGE)

Synonym(s):
SOD, Superoxide: superoxide oxidoreductase
CAS Number:
Enzyme Commission number:
Número EC:
Número MDL:
NACRES:
NA.54

linha de produto

BioUltra

Nível de qualidade

200

teor

≥97% (SDS-PAGE)

forma

lyophilized powder

specific activity

≥4,500 units/mg protein

peso molecular

32.5 kDa

composição

Protein, ≥95% biuret

doença(s) relevante(s)

arthritis

temperatura de armazenamento

−20°C

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Descrição geral

Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.

Aplicação

Superoxide Dismutase from bovine erythrocytes has been used in a study to assess activity parameters in adjuvant-induced arthritis. Superoxide Dismutase from bovine erythrocytes has also been used in a study to simplify the process of purifying superoxide dismutases using charge-controlled hydrophobic chromatography on 10-carboxydecyl Sepharose.

Embalagem

15000, 75000 units in glass bottle

Ações bioquímicas/fisiológicas

Catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice.

Definição da unidade

One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 °C in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.

Código de classe de armazenamento

12 - Non Combustible Liquids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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