SAB1401319

Anti-PTGDR antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

• Synonym(s): AS1, ASRT1, DP, DP1, MGC49004
• NACRES: NA.41

Properties

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• species reactivity: human
• technique(s): western blot: 1 μg/mL
• nº de adesão NCBI: NM_000953
• nº de adesão UniProt: Q13258
• enviado em: dry ice
• temperatura de armazenamento: −20°C
• Gene Information: human ... PTGDR(5729)

Description

Descrição geral

The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. (provided by RefSeq)

Imunogênio

PTGDR (NP_000944.1, 1 a.a. ~ 359 a.a) full-length human protein.

Sequence
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL

forma física

Solution in phosphate buffered saline, pH 7.4

Safety Information

• Código de classe de armazenamento: 10 - Combustible liquids
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable