SAB3700880

Anti-Rabbit IgG (H+L), highly cross adsorbed-Biotin antibody produced in goat

affinity isolated antibody, lyophilized powder

• NACRES: NA.46

Properties

• fonte biológica: goat
• conjugado: biotin conjugate
• forma do anticorpo: affinity isolated antibody
• antibody product type: secondary antibodies
• clone: polyclonal
• forma: lyophilized powder
• species reactivity: rabbit
• should not react with: hamster, goat, horse, guinea pig, bovine, sheep, mouse, rat, chicken, human
• technique(s): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• enviado em: wet ice
• temperatura de armazenamento: 2-8°C

Description

Descrição geral

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a gamma (γ) heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical (called Fab fragments) and contain the antigen-binding activity. The third fragment (called Fc fragment) does not possess antigen-binding activity, but binds to cells and effector molecules. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants.

Especificidade

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rabbit IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Biotin, Anti-Goat Serum, Rabbit IgG and Rabbit Serum. No reaction was observed against Bovine, Chicken, Goat, Guinea Pig, Hamster, Horse, Human, Mouse, Rat and Sheep Serum Proteins.

Imunogênio

Rabbit IgG whole molecule

propriedades físicas

Antibody format: IgG

forma física

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Reconstituição

Reconstitute with 1.0 mL deionized water (or equivalent).

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictogramas: GHS06,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H302 - H311 - H411
• Declarações de precaução: P280 - P301 + P312 + P330 - P302 + P352 + P312
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2
• Perigos de suplementos: EUH032
• Código de classe de armazenamento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable