• SAB4200476
All Photos(2)



Anti-ALIX antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

Anti-AIP1, Anti-ALG-2 interacting protein 1, Anti-DRIP4, Anti-HP95, Anti-PDCD6IP, Anti-apoptosis-linked gene 2-interacting protein X, Anti-dopamine receptor interacting protein 4, Anti-programmed cell death 6 interacting protein

fonte biológica


Nível de qualidade



forma do anticorpo

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

peso molecular

antigen ~95 kDa

species reactivity

mouse, human


~1.0 mg/mL


immunoprecipitation (IP): 5-10 μg using lysates of human Jurkat cells.
western blot: 2.5-5 μg/mL using whole extracts of mouse A20 cells.

nº de adesão UniProt

enviado em

dry ice

temperatura de armazenamento


Gene Information

human ... PDCD6IP(10015)
mouse ... Pdcd6ip(18571)

Descrição geral

The gene PDCD6IP (programmed cell death 6 interacting protein), also known as ALIX (apoptosis-linked gene 2-interacting protein X), is mapped to human chromosome 3p22.1 The protein has a crescent-shaped Bro1 domain, V-shaped V domain and a proline-rich region.


peptide corresponding to an internal region of human ALIX/ PDCD6IP, conjugated to KLH. The corresponding sequence is identical in monkey, bovine and dog and differs by 2 amino acids in mouse and rat.


Anti-ALIX antibody produced in rabbit has been used in immunoprecipitation and immunoblotting.


200 μL

Ações bioquímicas/fisiológicas

ALIX (Apoptosis-linked gene 2 (ALG-2)-interacting protein X binds to endophilins, proteins that regulate membrane shape during endocytosis. Over-expression of ALIX and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death.
PDCD6IP (programmed cell death 6 interacting protein) interacts with PDCD6, a protein involved in apoptosis. It also participates in intraluminal endosomal vesicle biogenesis, viral budding and cytokinetic abscission. PDCD6IP is a part of the ESCRT (endosomal sorting complexes required for transport) machinery.

forma física

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

12 - Non Combustible Liquids



Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service