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SAB4500797
Anti-AKT antibody produced in rabbit
affinity isolated antibody
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Synonym(s):
AKT1 kinase, AKT, PKB, kinase Akt1, C-AKT
Número MDL:
NACRES:
NA.41
fonte biológica
rabbit
Nível de qualidade
100
conjugado
unconjugated
forma do anticorpo
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
forma
buffered aqueous solution
peso molecular
antigen 55 kDa
species reactivity
rat, human, mouse
concentração
~1 mg/mL
technique(s)
ELISA: 1:1000
western blot: 1:500-1:1000
nº de adesão NCBI
nº de adesão UniProt
enviado em
wet ice
temperatura de armazenamento
−20°C
Gene Information
human ... AKT1(207)
Descrição geral
Anti-AKT Antibody detects endogenous levels of total AKT protein.
AKT serine/threonine kinase 1 (AKT1), also called as v-akt murine thymoma viral oncogene homolog 1 or protein kinase B α (PKB-α), is encoded by the gene mapped to human chromosome 14q32. It is highly expressed in liver, muscle and adipocytes. The encoded protein is a member of the AKT family, which is characterized with an amino-terminal pleckstrin homology (PH) domain, a short α-helical linker and a carboxyl-terminal kinase domain.
AKT serine/threonine kinase 1 (AKT1), also called as v-akt murine thymoma viral oncogene homolog 1 or protein kinase B α (PKB-α), is encoded by the gene mapped to human chromosome 14q32. It is highly expressed in liver, muscle and adipocytes. The encoded protein is a member of the AKT family, which is characterized with an amino-terminal pleckstrin homology (PH) domain, a short α-helical linker and a carboxyl-terminal kinase domain.
Imunogênio
The antiserum was produced against synthesized peptide derived from human Akt.
Immunogen Range: 90-139
Immunogen Range: 90-139
Aplicação
Anti-AKT antibody produced in rabbit has been used in Western Blotting.
Ações bioquímicas/fisiológicas
AKT serine/threonine kinase 1 (AKT1) acts as a regulator of cell-survival and anti-apoptotic functions. This protein has a crucial role in tumorigenesis. Mutations in the gene are associated with the pathogenesis of prostate cancer (PC). Elevated expression of the gene has been observed in human gastric cancer. Aberrations in AKT1 signaling leads to the development of schizophrenia.
Características e benefícios
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forma física
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de classe de armazenamento
12 - Non Combustible Liquids
WGK
nwg
Ponto de fulgor (ºF)
Not applicable
Ponto de fulgor (ºC)
Not applicable
Certificate of Analysis
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Certificate of Origin
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