SAB4501956

Sigma-Aldrich

Anti-Nibrin antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):
NBN, Cell cycle regulatory protein P95, NIJMEGEN BREAKAGE syndrome protein 1, NIBRIN, NBS
Número MDL:

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

peso molecular

antigen 84 kDa

species reactivity

human

concentração

~1 mg/mL

aplicação(ões)

ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

conjugado

unconjugated

nº de adesão NCBI

nº de adesão UniProt

enviado em

wet ice

temperatura de armazenamento

−20°C

Gene Information

human ... NBN(4683)

Descrição geral

Anti-Nibrin Antibody detects endogenous levels of total Nibrin protein.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Nibrin.

Immunogen Range: 251-300

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

storage_class_code

12 - Non Combustible Liquids

WGK Alemanha

nwg

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Certificado de origem

Yuki Yamamoto et al.
Cancer research, 74(14), 3707-3715 (2014-05-17)
Failure to expeditiously repair DNA at sites of double-strand breaks (DSB) ultimately is an important etiologic factor in cancer development. NBS1 plays an important role in the cellular response to DSB damage. A rare polymorphic variant of NBS1 that resulted...
Eui Young So et al.
Cancer biology & therapy, 15(7), 906-910 (2014-04-24)
The bone marrow (BM) is one of the organs that is sensitive to acute exposure of ionizing radiation (IR); however, the mechanism of its high sensitivity to IR remains to be elucidated. BM is differentiated into dendritic cells (DC) with...
Bárbara Alcaraz Silva et al.
The Journal of biological chemistry, 289(33), 22771-22784 (2014-07-02)
Chromosome ends contain nucleoprotein structures known as telomeres. Damage to chromosome ends during interphase elicits a DNA damage response (DDR) resulting in cell cycle arrest. However, little is known regarding the signaling from damaged chromosome ends (designated here as "TIPs")...

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