Merck
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SAB4700092

Sigma-Aldrich

Monoclonal Anti-CD9 antibody produced in mouse

clone MEM-61, purified immunoglobulin, buffered aqueous solution

NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

purified immunoglobulin

antibody product type

primary antibodies

clone

MEM-61, monoclonal

forma

buffered aqueous solution

species reactivity

human

concentração

1 mg/mL

technique(s)

flow cytometry: suitable

Isotipo

IgG1

nº de adesão NCBI

nº de adesão UniProt

enviado em

wet ice

temperatura de armazenamento

2-8°C

Gene Information

human ... CD9(928)

Descrição geral

CD9 (cluster of differentiation 9) is a human cell surface antigen. CD9 gene contains 8 exons extending over a length of 20kb on genomic DNA.The gene is mapped to human chromosome 2q12-pter. The encoded protein has a molecular weight of 24kDa and is expressed mainly on B-lineage-derived acute lymphoblastic leukemia cells and developing B lymphocytes.The protein is also present in blood platelets, neuroblastoma cell lines, normal and transformed epithelia, peripheral glia and neurons. CD9 antigen belongs to the transmembrane 4 superfamily (TM4SF) and is characterized with two external loops and four hydrophobic domains of membrane-spanning length.

Imunogênio

Pre-B cell line NALM-6

Aplicação

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Ações bioquímicas/fisiológicas

Members of transmembrane 4 superfamily (TM4SF) including CD9 (cluster of differentiation 9) plays a vital role in cell proliferation, activation, motility and tumor cell metastasis. CD9 facilitates platelet activation and aggregation. The encoded protein also plays a major role in the amplification of a motorgenic signal in B cells includingβ1 integrins and the activation of protein tyrosine kinases. CD9 interacts with GM3 and downregulates tumor cell motility. CD9 and CD81 stimulate muscle cell fusion and aids in myotube maintenance.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

12 - Non Combustible Liquids

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificate of Analysis

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Certificate of Origin

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