Merck
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SAB4700424

Sigma-Aldrich

Monoclonal Anti-CD326-FITC antibody produced in mouse

clone VU-1D9, purified immunoglobulin, buffered aqueous solution

Synonym(s):
Anti-EPCAM
NACRES:
NA.44

fonte biológica

mouse

Nível de qualidade

100

conjugado

FITC conjugate

forma do anticorpo

purified immunoglobulin

antibody product type

primary antibodies

clone

VU-1D9, monoclonal

forma

buffered aqueous solution

species reactivity

human

technique(s)

flow cytometry: suitable

Isotipo

IgG1

nº de adesão NCBI

nº de adesão UniProt

enviado em

wet ice

temperatura de armazenamento

2-8°C

Gene Information

human ... EPCAM(4072)

Descrição geral

Epithelial cell adhesion molecule (EpCAM) or cluster of differentiation 326 (CD326), is encoded by the 14kb GA733-2 gene mapped to human chromosome 2p21. Human CD326 expression is restricted to epithelia of colon, small intestine, lung, kidney, thymus, liver, pancreas, stomach. It is also expressed in several cancers, progenitor and stem cells. CD326 is a transmembrane glycoprotein characterized with an ectodomain, one transmembrane domain and a 26 residual cytoplasmic domain.
The mouse monoclonal antibody VU-1D9 recognizes an epitope within EGF-like domain I of CD326 / EpCAM, a marker of epithelial lineages. This antibody strongly stains various normal epithelial cells and carcinomas.

Imunogênio

Small cell lung carcinoma cell line H69

Aplicação

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

Ações bioquímicas/fisiológicas

Cluster of differentiation 326 (CD326) is a transmembrane glycoprotein, involved in several cellular functions, such as epithelial-specific intercellular cell–adhesion, cell signaling, migration, proliferation and differentiation. CD326 is a dominant surface antigen mapped on human colon carcinoma. It has potential as a diagnostic marker for several carcinomas, including epithelial ovarian cancer (EOC). CD326 is considered to be a potential target for cancer treatment. CD326 with the help of components of wnt signal transduction pathway plays a vital role in stem cell signaling.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

10 - Combustible liquids

WGK

WGK 2

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificate of Analysis

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Certificate of Origin

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