SAB5700777

Anti-ALIX/PDCD6IP antibody produced in rabbit

• Synonym(s): AIP1, ALIX, DRIP4, HP95, PDCD6IP

Properties

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 30; 96
• species reactivity: human, mouse, rat
• concentração: 3.76 mg/ml
• technique(s): immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200; western blot: 1:200-1:2000
• nº de adesão UniProt: Q8WUM4
• enviado em: wet ice
• temperatura de armazenamento: −20°C
• Gene Information: human ... PDCD6IP(10015)

Description

Descrição geral

This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.

Imunogênio

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALIX / PDCD6IP (NP_037506.2).

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• WGK: WGK 1
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable