SML0425

Caspofungin diacetate

≥97% (HPLC)

• Synonym(s): 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0
• Empirical Formula (Hill Notation): C₅₂H₈₈N₁₀O₁₅ · 2C₂H₄O₂
• CAS Number: 179463-17-3
• Molecular Weight: 1213.42
• ID de substância PubChem: 329825420
• NACRES: NA.77

Properties

• Nível de qualidade: 100
• teor: ≥97% (HPLC)
• forma: powder
• cor: white to beige
• solubilidade: H₂O: 15 mg/mL (clear solution)
• enviado em: wet ice
• temperatura de armazenamento: −20°C
• SMILES string: CC([O-])=O.CC([O-])=O.CC[C@H](C)C[C@H](C)CCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](NCC[NH3+])NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c4ccc(O)cc4)[C@H](O)CC[NH3+]
• InChI: 1S/C52H88N10O15.2C2H4O2/c1-5-28(2)24-29(3)12-10-8-6-7-9-11-13-39(69)56-34-26-38(68)46(55-22-21-54)60-50(75)43-37(67)19-23-61(43)52(77)41(36(66)18-20-53)58-49(74)42(45(71)44(70)31-14-16-32(64)17-15-31)59-48(73)35-25-33(65)27-62(35)51(76)40(30(4)63)57-47(34)72;2*1-2(3)4/h14-17,28-30,33-38,40-46,55,63-68,70-71H,5-13,18-27,53-54H2,1-4H3,(H,56,69)(H,57,72)(H,58,74)(H,59,73)(H,60,75);2*1H3,(H,3,4)/t28-,29+,30+,33+,34-,35-,36+,37-,38+,40-,41-,42-,43-,44-,45-,46-;;/m0../s1
• InChI key: OGUJBRYAAJYXQP-IJFZAWIJSA-N

Description

Aplicação

Caspofungin, aechinocandin, a lipophilic antifungal drug and α β-1,3-D-glucan synthesis antagonist, is used in fungal cell wall biosynthesis research to study the role of β-1,3-D-glucans in cell wall integrity and fungal survival under various environmental and chemical stresses.

Embalagem

5, 25 mg in glass bottle

Ações bioquímicas/fisiológicas

Caspofungin is an echinocandin antifungal that inhibits 1,3-β-D-glucan synthase, which is required for cell wall synthesis, thereby disturbing the integrity of the fungal cell wall.

Safety Information

• Código de classe de armazenamento: 11 - Combustible Solids
• WGK: WGK 3
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable