Merck
  • SML3019
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SML3019

Sigma-Aldrich

TH1760

≥98% (HPLC)

Synonym(s):
6-{[4-(1H-indole-5-carbonyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzoxazol-2-one
Empirical Formula (Hill Notation):
C20H18N4O5S
CAS Number:
Molecular Weight:
426.45

Nível de qualidade

Ensaio

≥98% (HPLC)

forma

powder

cor

white to beige

solubilidade

DMSO: 2 mg/mL, clear

temperatura de armazenamento

2-8°C

SMILES string

O=S(C1=CC(O2)=C(C=C1)NC2=O)(N3CCN(CC3)C(C4=CC5=C(C=C4)NC=C5)=O)=O

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TH1760 ≥98% (HPLC)

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SML3019

TH1760

TH5487 ≥98% (HPLC)

Sigma-Aldrich

SML2531

TH5487

TH-257 ≥98% (HPLC)

Sigma-Aldrich

SML2275

TH-257

TH1020 ≥95% (HPLC)

Sigma-Aldrich

SML1741

TH1020

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

form

powder

form

powder

form

powder

form

powder

color

white to beige

color

white to beige

color

white to beige

color

white to beige

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 3 mg/mL, clear (warmed)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

100

Ações bioquímicas/fisiológicas

TH1760 is a cell penetrant, potent and selective inhibitor of NUDT15 (NUDIX-type 15) that directly binds into the NUDT15 catalytic pocket. TH1760 sensitized cells to 6-thioguanine.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable


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