Merck
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SRP5316

Sigma-Aldrich

RIPK3, active, GST tagged human

PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):
RIP3
CAS Number:

fonte biológica

human

recombinante

expressed in baculovirus infected Sf9 cells

linha de produto

PRECISIO®

teor

≥70% (SDS-PAGE)

forma

buffered aqueous glycerol solution

specific activity

30-51 nmol/min·mg

peso molecular

~96 kDa

nº de adesão NCBI

application(s)

cell analysis

enviado em

dry ice

temperatura de armazenamento

−70°C

Gene Information

human ... RIPK3(11035)

Descrição geral

Receptor interacting serine/threonine kinase 3 (RIPK3)/RIP3 is a serine/threonine kinase. It belongs to the receptor-interacting protein family. RIPK3 is characterized with a conserved amino-terminal kinase domain, which is necessary for necrosis. The gene RIPK3 is mapped to human chromosome 14. The encoded protein is composed of 518 amino acids.

Ações bioquímicas/fisiológicas

Receptor interacting serine/threonine kinase 3 (RIPK3) activates necroptotic cell death and has a role in inflammatory signaling. The protein also functions in controlling viral infections, platelet functions, hemostasis and thrombosis. RIPK3 is highly expressed during cutaneous wound repair and also stimulates interleukin-1 β production.

forma física

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Nota de preparo

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Informações legais

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Código de classe de armazenamento

10 - Combustible liquids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificate of Analysis

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Certificate of Origin

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SDS

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