Merck
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SRP6172

Sigma-Aldrich

IL-4 human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Synonym(s):
B-cell stimulatory factor 1 (BSF-1), BCGF, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra
NACRES:
NA.32

fonte biológica

human

recombinante

expressed in HEK 293 cells

teor

≥95% (SDS-PAGE)

forma

lyophilized

peso molecular

(14 and 19 kDa, monomer)

embalagem

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

nº de adesão NCBI

enviado em

dry ice

temperatura de armazenamento

−70°C

Gene Information

human ... IL4(3565)

Descrição geral

Interleukin-4 (IL-4) is a pleiotropic cytokine and a potent lymphoid cell growth factor. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The gene encoding this protein is localized on human chromosome 5q31.1. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Ações bioquímicas/fisiológicas

Interleukin-4 (IL-4) stimulates the growth and survivability of certain B cells and T cells. The interleukin 4 receptor also binds to interleukin-13 (IL-13), which may contribute to many overlapping functions of this cytokine and IL-13. STAT6 (signal transducer and activator of transcription-6) has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This protein exhibits anti-inflammatory responses and has a role in immune processes by protecting against intracellular pathogens.

forma física

Lyophilized from a solution of 20 mM Tris-HCl, pH 7.4, with 300 mM NaCl.

Nota de preparo

Centrifuge the vial prior to opening.

Reconstituição

Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificate of Analysis

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Certificate of Origin

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