Merck
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T2501

Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

≥98% (HPLC), powder

Synonym(s):
3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4
Linear Formula:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
CAS Number:
Molecular Weight:
888.93
Beilstein:
5721845
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.32

fonte biológica

synthetic (organic)

Nível de qualidade

200

esterilidade

non-sterile

teor

≥98% (HPLC)

forma

powder

pf

207-210 (dec.) (lit.)

solubilidade

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

enviado em

ambient

temperatura de armazenamento

−20°C

SMILES string

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

Gene Information

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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Embalagem

1, 5 g in glass bottle

Ações bioquímicas/fisiológicas

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Nota de preparo

L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

STOT RE 1

Código de classe de armazenamento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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