Merck
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T8158

Sigma-Aldrich

Transferrin human

powder, BioReagent, suitable for cell culture

Synonym(s):
Siderophilin, partially saturated
CAS Number:
Número EC:
Número MDL:
NACRES:
NA.75

linha de produto

BioReagent

Nível de qualidade

teor

≥98%

forma

powder

concentração

~25 mM

technique(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested
hepatitis and HIV antibody, none detected

solubilidade

H2O: 50 mg/mL

nº de adesão UniProt

enviado em

ambient

temperatura de armazenamento

−20°C

Gene Information

human ... TF(7018)

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This Item
T4132T0665T3309
Sigma-Aldrich

Sigma-Aldrich

T8158

Transferrin human

holo-Transferrin human ≥98%

Sigma-Aldrich

T4132

holo-Transferrin human

holo-Transferrin human powder, BioReagent, suitable for cell culture, ≥97%

Sigma-Aldrich

T0665

holo-Transferrin human

Sigma-Aldrich

Sigma-Aldrich

T3309

Transferrin human

form

powder

form

powder

form

powder

form

powder

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | stem cell: suitable

impurities

endotoxin, tested, hepatitis and HIV antibody, none detected

impurities

HIV, hepatitis B and hepatitis C, none detected

impurities

HIV and HBsAg, none detected, endotoxin, tested

impurities

≤1.0 EU/mg endotoxin

solubility

H2O: 50 mg/mL

solubility

-

solubility

H2O: 50 mg/mL

solubility

-

shipped in

ambient

shipped in

-

shipped in

ambient

shipped in

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Descrição geral

Transferrin is a glycoprotein with a branched carbohydrate chain, having two sites for ferric ion binding in its polypeptide chain.

Aplicação

Transferrin human has been used:
  • to incubate human proximal tubule cells (HKC) - 8 cells along with IgG for the examination of albumin specificity
  • as a supplement in serum-containing/devoid medium for human thyroid cell culture
  • as a target glycoprotein to develop an in-gel hydrazinolysis method

Ações bioquímicas/fisiológicas

Transferrin mediates iron transportation from plasma to cells. The iron-bound transferrin are of three forms: monoferric A/B transferrin and diferric transferrin. The transferrin binds to specific cell surface receptors and are internalized by endocytosis. Once inside, the iron is released into the cells and the iron-free transferrin, also referred to as apotransferrin, is exocytosed outside the cell without being degraded. Transferrin is known to deliver iron to cells in a physiologically safe and effective form.

Outras notas

Partially iron-saturated

Nota de preparo

Heat treated at 60 °C for ten hours.

Nota de análise

Purity by agarose electrophoresis.

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

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Product Information Sheet

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