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Xanthine Oxidase from bovine milk

Grade I, ammonium sulfate suspension, ≥0.4 units/mg protein

XOD, Xanthine:oxygen oxidoreductase
CAS Number:
Enzyme Commission number:
Número EC:
Número MDL:


Grade I

Nível de qualidade



ammonium sulfate suspension

specific activity

≥0.4 units/mg protein

atividade externa

uricase ≤0.5%

enviado em

wet ice

temperatura de armazenamento


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Descrição geral

Xanthine Oxidase (XOD) is a metal flavoprotein. It has flavin adenine dinucleotide (FAD), molybdenum and iron in the ratio 2:2:8. This homodimer has a molecule weight of 290kDa. It is a member of the molybdenum-protein family. This enzyme consists of two separated substrate-binding sites.
Formerly E.C.


Xanthine Oxidase from bovine milk has been used:
  • in the preparation of xanthine oxidase (XO) solution for 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO)-spin trapping assay
  • in in vitro XO assay for screening Vietnamese medicinal plants for XO inhibitory activity
  • as a standard to determine XO activity
  • as a standard to test the synergistic effect of docosahexaenoic acid (DHA)


5, 25 units in serum bottle

Ações bioquímicas/fisiológicas

Hydroxylation of hypoxanthine to xanthine and xanthine to uric acid is catalyzed by xanthinebb oxidase (XO) enzyme.
Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.
Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c.

Definição da unidade

One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.

forma física

Suspension in 2.3 M (NH4)2SO4 containing 1 mM sodium salicylate

Nota de análise

Protein determined by biuret


Health hazard

Palavra indicadora


Frases de perigo

Declarações de precaução

Classificações de perigo

Resp. Sens. 1

Código de classe de armazenamento

11 - Combustible Solids



Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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