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Accurate characterization of carcinogenic DNA adducts using MALDI tandem time-of-flight mass spectrometry.
Barnes C A and Chiu N H
International Journal of Mass Spectrometry, 279(2-3), 170-175 (2009)
M J Nogueiras et al.
Analytical and bioanalytical chemistry, 377(7-8), 1202-1206 (2003-10-11)
The human toxic syndrome, diarrhetic shellfish poisoning (DSP), is caused by polyether toxins that are present in bivalve molluscs but originate from some species of marine phytoplankton. During the last few years different HPLC methods with fluorescence detection (FLD) have...
Dmitri V Zagorevskii et al.
Journal of the American Society for Mass Spectrometry, 17(9), 1265-1270 (2006-07-01)
Oligonucleotides synthesized on a montmorillonite catalyst were analyzed directly. By mixing the catalyst with a matrix (2,4,6-trihydroxyacetophenone or 6-aza-2-thiothymine) and dibasic ammonium citrate, higher molecular weight products were detected compared with "classical" methods such as gel electrophoresis and HPLC with...
Shi-Jun Dong et al.
The international journal of biochemistry & cell biology, 68, 33-41 (2015-08-19)
During the industrial bioethanol fermentation, Saccharomyces cerevisiae cells are often stressed by bacterial contaminants, especially lactic acid bacteria. Generally, lactic acid bacteria contamination can inhibit S. cerevisiae cell growth through secreting lactic acid and competing with yeast cells for micronutrients...
Jason P Schrum et al.
Journal of the American Chemical Society, 131(40), 14560-14570 (2009-09-18)
The development of a sequence-general nucleic acid copying system is an essential step in the assembly of a synthetic protocell, an autonomously replicating spatially localized chemical system capable of spontaneous Darwinian evolution. Previously described nonenzymatic template-copying experiments have validated the...
Dorothea F K Rawn et al.
Journal of chromatography. A, 1080(2), 148-156 (2005-07-13)
A rapid and simple method for confirmation of the diarrhetic shellfish poisons (DSP): okadaic acid (OA), dinophysistoxin-1 (DTX-1) and dinophysistoxin-2 (DTX-2) using fluorescence detection following derivatization with 9-chloromethylanthracene, has been established as an alternate to LC/MS. Exposure of the anthrylmethyl...
Ying Zhang et al.
Colloids and surfaces. B, Biointerfaces, 44(2-3), 104-109 (2005-07-26)
Polymeric micelles based on amphiphilic diblock copolymers methoxy poly(ethylene glycol)-polylactide with various hydrophobic lengths were designed as carriers of poorly water-soluble anticancer drug methotrexate (MTX). Relationship between physicochemical characteristics of micelles and release behavior was explored. The critical micelle concentration...
J F Lawrence et al.
Journal of chromatography. A, 721(2), 359-364 (1996-01-19)
The reagent 9-chloromethylanthracene was evaluated for derivatization of the diarrhetic shellfish poisons, okadaic acid and dinophysistoxin-1 (DTX-1), to form fluorescent products separable by liquid chromatography. The toxins were reacted with the reagent in acetonitrile in the presence of tetramethylammonium hydroxide...
Virginia De Cesare et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(4) (2021-01-23)
The reversibility of ubiquitination by the action of deubiquitinating enzymes (DUBs) serves as an important regulatory layer within the ubiquitin system. Approximately 100 DUBs are encoded by the human genome, and many have been implicated with pathologies, including neurodegeneration and...
Zhenming Xie et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 857(1), 53-58 (2007-08-21)
A rapid and sensitive RP-HPLC method with fluorescence detection has been developed for the quantitative analysis of trace amounts of monofluoroacetate (MFA) in biological samples as serum, food and meat. 9-Chloromethylanthracene (9-CMA) is used as the fluorescence labeling reagent. Samples...
N. Kornblum et al.
Journal of the American Chemical Society, 96, 590-590 (1974)
Zhenming Xie et al.
Journal of chromatographic science, 50(6), 464-468 (2012-04-14)
A simple and sensitive high-performance liquid chromatography (HPLC) method is proposed for the analysis of some carboxylic acids in food samples and the environment. The use of 9-chloromethyl anthracene as a fluorescence-labeling reagent has been investigated. The derivatization reagent reacts...
Lorina Gjonaj et al.
Organic & biomolecular chemistry, 13(21), 6059-6065 (2015-05-08)
A new method for the selective chemical modification of DNA at cytosine nucleobases using alkoxy- and benzyloxyamines is presented. It is shown that in particular benzyloxyamines are effective DNA modifying agents, giving rise to almost exclusive formation of the mono...
W.D. Korte
Journal of Chromatography A, 243, 153-153 (1982)
Study of matrix and polymer substrate in MALDI-TOF mass spectrometry of DNA.
Kim Y and Hurst G B
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 70(3), 219-228 (2001)
Microwave-assisted ultrafast and facile synthesis of fluorescent carbon nanoparticles from a single precursor: preparation, characterization and their application for the highly selective detection of explosive picric acid.
Sun X, et al.
Journal of Materials Chemistry, 4(11), 4161-4171 (2016)
Ewa Radzikowska et al.
Organic & biomolecular chemistry, 13(1), 269-276 (2014-11-05)
Chimeric oligonucleotides containing phosphodiester and phosphorothioate linkages have been obtained using the solid phase synthesis. The oligonucleotide parts possessing natural internucleotide phosphate bonds were assembled using commercially available nucleoside 3'-O-(2-cyanoethyl-N,N-diisopropylamino)phosphoramidites 7 whereas the phosphorothioate segment was built using nucleoside 3'-O-(2-thio-1,3,2-oxathiaphospholanes)...
S Vollmer et al.
Organic & biomolecular chemistry, 13(20), 5734-5742 (2015-04-23)
Triplexes with a gap in the purine strand have been shown to bind adenosine or guanosine derivatives through a combination of Watson-Crick and Hoogsteen base pairing. Rigidifying the binding site should be advantageous for affinity. Here we report that clamps...