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Jeremy R Keown et al.
The Biochemical journal, 464(3), 413-423 (2014-09-24)
Most plants contain two isoforms of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) activase (Rca), a chloroplast protein that maintains the activity of Rubisco during photosynthesis. The longer (α-) Rca isoform has previously been shown to regulate the activity of Rubisco in response to...
R N Tsepilov et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (2)(2), 12-20 (2013-06-29)
Selection of high-mucoid morphotype of Streptococcus equi subsp. zooepidemicus (Streptococcus zooepidemicus) and study of its morphological, physiological, biochemical and technological characteristics for providing increased secretion of hyaluronic acid (HA). Submerged cultivation was performed in 100 ml glass flasks without baffles...
Long-Liu Lin et al.
Biochimica et biophysica acta, 1844(9), 1523-1529 (2014-05-02)
γ-Glutamyltranspeptidases (γ-GTs) cleave the γ-glutamyl amide bond of glutathione and transfer the released γ-glutamyl group to water (hydrolysis) or acceptor amino acids (transpeptidation). These ubiquitous enzymes play a key role in the biosynthesis and degradation of glutathione, and in xenobiotic...
Nikolai N Sluchanko et al.
Archives of biochemistry and biophysics, 549, 32-39 (2014-04-01)
Members of the 14-3-3 protein family interact with hundreds of different, predominantly phosphorylated, proteins. 14-3-3 dimers are prevalent but exist at the equilibrium with the monomers. Our previous studies using the engineered monomeric 14-3-3ζ (14-3-3ζm) showed that 14-3-3ζ monomer retained...
M L Selley et al.
Neurobiology of aging, 23(3), 383-388 (2002-04-18)
There is evidence that increased blood concentrations of homocysteine may be a risk factor for Alzheimer's disease. (E)-4-hydroxy-2-nonenal (HNE) is a neurotoxic product of lipid peroxidation that is increased in the ventricular fluid and brains of patients with Alzheimer's disease....
Tatsuya Yoshida et al.
Japanese journal of clinical oncology, 44(4), 346-354 (2014-02-08)
Magnesium supplementation has been reported to have a nephroprotective effect on cisplatin-induced renal dysfunction, but little evidence exists regarding the effect of magnesium preloading before cisplatin administration. We started to include magnesium preloading (8 mEq) in cisplatin-containing treatment regimens in...
C Syburra et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 71(3), 112-115 (1999-12-28)
It is well known that brain and nervous system cells are prone to oxidative damage because of their relatively low content of antioxidants, especially enzymatic ones, and of the high levels of both membrane polyunsaturated fatty acids (PUFA) and iron...
P A Bakumov et al.
Meditsina truda i promyshlennaia ekologiia, (3)(3), 41-43 (2013-06-22)
The possibility of magnesium deficiency correction was investigated in medical personnel with metabolic syndrome. It was shown that treatment with drugs containing magnesium leads to a decrease the cholesterol level.
Chamani P M Marasinghe Wadige et al.
Aquatic toxicology (Amsterdam, Netherlands), 149, 83-93 (2014-03-01)
Lead entering aquatic ecosystems adsorbs to sediments and has the potential to cause adverse effects on the health of benthic organisms. To evaluate the freshwater bivalve Hyridella australis as a bioindicator for sediment toxicity, their exposure-dose and response to lead...
Zhichao Liu et al.
PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated...
Jian-ping Jia et al.
Chinese medical journal, 117(8), 1161-1164 (2004-09-14)
An important aspect of Alzheimer's disease (AD) is loss or impairment of cholinergic neurons. It is controversial whether there is a similar cholinergic impairment and cerebral deficit of acetylcholine (ACh) in the case of vascular dementia (VD). The purpose of...
William A Beard et al.
Biochemistry, 53(17), 2768-2780 (2014-04-11)
DNA polymerase (pol) β is a small eukaryotic DNA polymerase composed of two domains. Each domain contributes an enzymatic activity (DNA synthesis and deoxyribose phosphate lyase) during the repair of simple base lesions. These domains are termed the polymerase and...
Rock's power to mop up carbon revisited.
Daniel Cressey
Nature, 505(7484), 464-464 (2014-01-24)
Hangyuan Guo et al.
Herz, 29(3), 299-303 (2004-05-29)
This study sought to clarify the relationship between the degree of intracellular magnesium deficiency and the frequency of anginal attacks in women with variant angina. We evaluated the intracellular and extracellular magnesium status of twelve women with variant angina: group...
E J Pappert et al.
Neurology, 47(4), 1037-1042 (1996-10-01)
To determine if ventricular cerebrospinal fluid (vCSF) alpha-tocopherol levels in Parkinson's disease (PD) patients can be increased by oral alpha-tocopherol supplementation and whether vCSF levels are linearly related to plasma alpha-tocopherol levels. In spite of its putative neuroprotective properties, alpha-tocopherol...
Tahir Rafique et al.
Water environment research : a research publication of the Water Environment Federation, 85(7), 579-586 (2013-08-16)
The role of seawater dilution, along with other water-quality components, has been studied to determine the causes of spatial distribution of high fluoride concentrations in the groundwater of the Diplo sub-district, Thar Desert, Pakistan. Fluoride ion concentration ranges of up...
M A Lovell et al.
Archives of neurology, 58(3), 392-396 (2001-03-20)
Markers of oxidative stress are increased in cerebrospinal fluid (CSF) of patients with Alzheimer disease (AD), although none of those reported are appropriate diagnostic markers because of the overlap between patients with AD and control subjects. To determine the ratio...
A Moser et al.
Journal of the neurological sciences, 131(2), 183-189 (1995-08-01)
We could identify the MPTP-like compound and isoquinoline derivative N-methyl-norsalsolinol (2-MDTIQ) in cerebrospinal fluid (CSF) of patients with Parkinson's disease. The presence of 2-MDTIQ negatively correlated with the disease duration. In order to study the relationship between presence of 2-MDTIQ...
Treatment of pediatric hypomagnesaemia: a fast and safe way.
Ismail El-Beshlawi
Pediatric blood & cancer, 61(7), 1156-1156 (2013-09-04)
Małgorzata Kiełczykowska et al.
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 58(2), 281-284 (2004-08-25)
Lithium is used in medicine. However, its administration can have negative side effects, disturb the water-electrolyte equilibrium and affect the level of essential elements. For these reasons the influence of oral lithium intoxication at the dose of 150 mg Li...
H S Na et al.
Anaesthesia, 69(12), 1314-1321 (2014-08-19)
We investigated the effects of magnesium sulphate on blood coagulation profiles using rotational thromboelastometry in patients undergoing laparoscopic colorectal cancer surgery. Patients were randomly allocated to the magnesium group (n = 22) or control group (n = 22). The magnesium...
Na Yu et al.
Archives of biochemistry and biophysics, 564, 74-82 (2014-09-30)
Na(+)/Mg(2+) exchanger plays an important role in cardiovascular system, but the molecular mechanisms still largely remain unknown. The Solute Carrier family 41A1 (SLC41A1), a novel Mg(2+) transporter, recently was found to function as Na(+)/Mg(2+) exchanger, which mainly regulates the intracellular...
Charles L Loprinzi et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(10), 997-1005 (2013-12-04)
Cumulative neurotoxicity is a prominent toxicity of oxaliplatin-based therapy. Intravenous calcium and magnesium have been extensively used to reduce oxaliplatin-induced neurotoxicity. This trial was designed to definitively test whether calcium/magnesium decreases oxaliplatin-related neurotoxicity. In all, 353 patients with colon cancer...
V K Kol'tover
Biofizika, 58(2), 257-263 (2013-06-13)
There is a great variety of chemical elements with magnetic and nonmagnetic isotopes in living cells. The question arises as to whether living cells can perceive the difference between magnetic and non-magnetic isotopes of chemical elements. It has been shown...
Limor Gortzak-Uzan et al.
The Journal of reproductive medicine, 50(11), 817-820 (2006-01-20)
To compare the effect of prolonged maternal intravenous MgSO4 administration on amniotic fluid and serum concentrations of magnesium over time in preterm labor patients. Patients at 24-34 weeks of singleton gestation who presented with contractions (> 8 in 60 minutes)...
Elena Fridman et al.
Harefuah, 152(3), 158-161 (2013-05-30)
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in premature infants who have needed mechanical ventilation and oxygen therapy. BPD is defined as the presence of persistent respiratory symptoms, the need for supplemental oxygen to treat hypoxemia, and...
Marta Guasch-Ferré et al.
The Journal of nutrition, 144(1), 55-60 (2013-11-22)
The relation between dietary magnesium intake and cardiovascular disease (CVD) or mortality was evaluated in several prospective studies, but few of them have assessed the risk of all-cause mortality, which has never been evaluated in Mediterranean adults at high cardiovascular...
Ask the doctors. I recently developed atrial fibrillation, and my doctor said it was because my magnesium level was low. What would cause this to happen?
Thomas Lee et al.
Harvard heart letter : from Harvard Medical School, 23(8), 2-2 (2013-08-07)
Thi Dong Phuong Nguyen et al.
Environmental technology, 35(9-12), 1378-1388 (2014-04-08)
The freshwater microalga Chlorella vulgaris was harvested by autoflocculation resulting from the precipitation of magnesium or calcium compounds induced by a slow increase in pH in the absence of CO2 input. Autoflocculation was tested in two culture media with, respectively...
Jamie D Murphy et al.
Middle East journal of anaesthesiology, 22(1), 11-20 (2013-07-10)
The efficacy of perioperative intravenous magnesium administration on postoperative opioid use, opioid-related side effects (e.g., nausea and vomiting) and pain are uncertain, as randomized controlled trials on this topic have reported disparate results. The objective of this systematic review is...
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