Showing 1-30 of 128 resultados for "

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Xuewen Fu et al.
Journal of nanoscience and nanotechnology, 13(12), 8245-8252 (2013-11-26)
A label-free electrochemical immunosensor, based on a gold nanoparticles (Au NPs)/silicon template/methylene blue (MB)/chitosan (CHIT) nanocomposite-modified electrode, was fabricated for the ultrasensitive detection of microcystin-LR (MC-LR). The nanocomposite film showed high binding affinity to the antibodies of MC-LR because gold...
Taek Lee et al.
Journal of nanoscience and nanotechnology, 13(9), 6020-6026 (2013-11-12)
In the present study, an nano-platform composed of Au nanodot arrays on which biomolecules could be self-assembled was developed and investigated for a stable bioelectronic device platform. Au nanodot pattern was fabricated using a nanoporous alumina template. Two different biomolecules...
Gavin J Churchyard et al.
The New England journal of medicine, 370(4), 301-310 (2014-01-24)
Tuberculosis is epidemic among workers in South African gold mines. We evaluated an intervention to interrupt tuberculosis transmission by means of mass screening that was linked to treatment for active disease or latent infection. In a cluster-randomized study, we designated...
E Jortzik et al.
Biochimica et biophysica acta, 1844(8), 1415-1426 (2014-01-21)
Glioblastoma, an aggressive brain tumor, has a poor prognosis and a high risk of recurrence. An improved chemotherapeutic approach is required to complement radiation therapy. Gold(I) complexes bearing phosphole ligands are promising agents in the treatment of cancer and disturb...
Tonguc O Tasci et al.
Journal of chromatography. A, 1365, 164-172 (2014-09-24)
Compared to other sub-techniques of field flow fractionation (FFF), cyclical electrical field flow fractionation (CyElFFF) is a relatively new method with many opportunities remaining for improvement. One of the most important limitations of this method is the separation of particles...
Yuying Zhang et al.
Journal of visualized experiments : JoVE, (95)(95), e52058-e52058 (2015-01-16)
Fluorescent nanoparticles (NPs) with desirable chemical, optical and mechanical properties are promising tools to label intracellular organelles. Here, we introduce a method using gold-BSA-rhodamine NPs to label the endo-lysosomal system of eukaryotic cells and monitor manipulations of host cellular pathways...
Shereen F Mossallam et al.
Experimental parasitology, 144, 14-21 (2014-06-15)
Through increased awareness and improved diagnostics, microsporidiosis has now been identified in a broader range of human populations; however current therapies are inconsistently effective. Recently, probiotics were determined as means for the control of intestinal parasitic infections through their secretory...
Jungsoo Kim et al.
Journal of nanoscience and nanotechnology, 13(5), 3737-3741 (2013-07-19)
Some composites of gold nanoparticles and graphite nanosheets were prepared by electrostatic interaction, and structurally and electrochemically characterized using X-ray diffraction, X-ray photoelectron spectroscopy, UVNis spectroscopy, transmission electron microscopy, and cyclic-voltammetry. Pristine graphite was chemically treated using aqueous acid solution...
Feng Geng et al.
Journal of biomedical nanotechnology, 10(7), 1205-1216 (2014-05-09)
Pharmacokinetics and bio-distribution are crucial factors affecting the performance of an intravenous drug. In this study, we explore the combined use of glucose and polyethylene glycol (PEG) ligands to further improve gold nanoparticle (GNP) pharmacokinetics and bio-distribution, with the aim...
Ying Sun et al.
Journal of nanoscience and nanotechnology, 14(6), 4078-4081 (2014-04-18)
Colloidal gold is extensively used for molecular sensing because that the surface plasmon resonance (SPR) bands are affected by changes in the dielectric properties in the close vicinity of these structures due to the binding of ligands to the corresponding...
Babak Mostafazadeh et al.
Pakistan journal of pharmaceutical sciences, 26(6), 1267-1270 (2013-11-06)
Mercury exposure is a health concern in the occupational settings like gold mining and chloralkali industries and blood and urine levels of mercury are used as exposure indicators. In this study, blood and urine concentrations of mercury were determined using...
Celina Yang et al.
Journal of nanoscience and nanotechnology, 14(7), 4813-4819 (2014-04-25)
The applications of nanoparticles (NPs) for improved therapeutics are at the forefront of cancer nanotechnology. Gold nanoparticles (GNPs) have been extensively used due to their ability to act as both an anticancer drug carrier in chemotherapy and as a dose...
Halvor Möller
Contact dermatitis, 47(2), 63-66 (2002-11-09)
Contact allergy to gold as demonstrated by patch testing is very common among patients with eczematous disease and seems to be even more frequent among patients with complaints from the oral cavity. There is a positive correlation between gold allergy...
Kaili Niu et al.
Journal of nanoscience and nanotechnology, 14(7), 5151-5156 (2014-04-25)
An immunochromatographic test strip using gold nanoparticles-staphylococcus aureus monoclonal antibody conjugates was developed for the rapid and convenient detection of staphylococcus aureus based on a double-antibody sandwich format. The detection limit and the detection rate of this test strip is...
Nidhi Gupta et al.
Journal of nanoscience and nanotechnology, 13(7), 5069-5079 (2013-08-02)
Core-shell morphology of silica (SiO2) coated CdS nanocomposites (SiO2@CdS) of different shapes have been made for better stability, luminescence and photochemical activity of CdS nanoparticles. A thin layer (thickness 1-1.4 nm) of SiO2 shell is deposited over CdS nanorods (CdS-NR)...
Priyatha Premnath et al.
Journal of biomedical nanotechnology, 10(6), 1061-1067 (2014-04-23)
Hybrid biomaterials are a combination of two or more different materials that work synergistically to produce superior properties. Nano structuring of such hybrid materials has also posed complications. In this study, we present, for the first time a nanofibrous hybrid...
Stacey N Barnaby et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(27), 9739-9744 (2014-06-21)
Small interfering RNA (siRNA) is a powerful and highly effective method to regulate gene expression in vitro and in vivo. However, the susceptibility to serum nuclease-catalyzed degradation is a major challenge and it remains unclear whether the strategies developed to...
Catalysis: Gold unleashes the power of three.
Christopher M B K Kourra et al.
Nature, 517(7535), 440-441 (2015-01-23)
Samudra Sengupta et al.
Nature chemistry, 6(5), 415-422 (2014-04-24)
Non-mechanical nano- and microscale pumps that function without the aid of an external power source and provide precise control over the flow rate in response to specific signals are needed for the development of new autonomous nano- and microscale systems....
James L Mallows
The Medical journal of Australia, 199(11), 813-814 (2013-12-18)
To examine the effect of an education campaign based around a gold coin fine on ordering of C-reactive protein (CRP) tests. A retrospective analysis of CRP test ordering before and after the intervention in the emergency department (ED) of a...
Divya Prakash et al.
Indian journal of experimental biology, 51(11), 969-972 (2014-01-15)
Gold nanoparticles (Au-NPs) were synthesized from chloroauric acid using cell free supernatant of Streptomyces sp. NK52 grown in nutrient broth. These nanoparticles were synthesized by varying pH and temperature of the reaction mixture and chloroauric acid concentration. The nanoparticles were...
Monic Shah et al.
Journal of nanoscience and nanotechnology, 14(1), 344-362 (2014-04-16)
This article reviews some of the recent biological applications of gold nanoparticles (GNPs) which have been discovered lately by individual studies all around the world. GNPs have emerged as a promising candidates for various biological applications due to their unique...
Amelie Heuer-Jungemann et al.
Nanoscale, 5(20), 9503-9510 (2013-08-29)
In the past decade gold nanoparticle-nucleic acid conjugates became progressively important for biomedical applications. Fluorophores attached to nucleic acid-gold nanoparticle conjugates have opened up a new era of biological sensing. The most promising advancement in this field was the invention...
Fengxian Zheng et al.
Journal of nanoscience and nanotechnology, 13(6), 3990-3998 (2013-07-19)
Gold nanoparticles (AuNPs) are of biomedical importance, such as delivery vectors. Therefore, we used all-atom molecular dynamic simulations to study the interaction of AuNPs with cell membrane (DMPC bilayer). We observed that the AuNPs adhered spontaneously on the surface of...
Chen Zhou et al.
Experimental biology and medicine (Maywood, N.J.), 238(11), 1199-1209 (2013-10-11)
Our fundamental understanding of cell biology and early diagnosis of human diseases have been greatly benefited from the development of fluorescent probes. Over the past decade, luminescent gold nanoparticles (AuNPs) with diverse structural parameters including particle size, surface ligands, valence...
Hwa Jung Noh et al.
Journal of nanoscience and nanotechnology, 13(12), 8229-8238 (2013-11-26)
Gold nanoparticles were green-synthesized using a glycosaminoglycan, chondroitin sulfate, as the reducing agent by mixing Au3+ and chondroitin sulfate under heating. Chondroitin sulfate-reduced gold nanoparticles were characterized by UV-Vis spectrophotometry, high resolution transmission electron microscopy and atomic force microscopy. The...
Germán Plascencia-Villa et al.
Journal of nanoscience and nanotechnology, 13(8), 5572-5579 (2013-07-26)
Self-assembled structures derived of viral proteins display sophisticated structures that are difficult to obtain with even advanced synthesis methods and the use of protein nanotubes for synthesis and organization of inorganic nanoarrays into well-defined architectures are here reported. Nanoparticle arrays...
Claudia Diletto et al.
Journal of nanoscience and nanotechnology, 13(7), 5215-5220 (2013-08-02)
Innovative hybrid nanocomposites based on a nanostructured block copolymer (BCP) matrix whose lamellar nanodomains are selectively loaded with metal nanoparticles, have been prepared. A symmetric poly(styrene-b-methylmethacrylate) (PS-b-PMMA) amorphous BCP showing a lamellar morphology has been employed. Thin films of PS-b-PMMA...
Huang Gao et al.
Science (New York, N.Y.), 346(6215), 1352-1356 (2014-12-17)
We report a low-cost, high-throughput benchtop method that enables thin layers of metal to be shaped with nanoscale precision by generating ultrahigh-strain-rate deformations. Laser shock imprinting can create three-dimensional crystalline metallic structures as small as 10 nanometers with ultrasmooth surfaces...
Jiajing Zhang et al.
Journal of nanoscience and nanotechnology, 14(6), 4124-4138 (2014-04-18)
Gold nanostructures with promising applications in biomedical field have attracted great attention. However, some fundamental questions other than the development of novel applications should be elucidated before they can actually serve as biomedicines in the clinic. Bio-safety is one of...