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Akiko Takagaki et al.
Archives of microbiology, 196(10), 681-695 (2014-06-21)
Two intestinal bacterial strains MT4s-5 and MT42 involved in the degradation of (-)-epigallocatechin (EGC) were isolated from rat feces. Strain MT4s-5 was tentatively identified as Adlercreutzia equolifaciens. This strain converted EGC into not only 1-(3, 4, 5-trihydroxyphenyl)-3-(2, 4, 6-trihydroxyphenyl)propan-2-ol (1)...
Sumit Bansal et al.
Natural product reports, 30(11), 1438-1454 (2013-09-24)
Extensive research on tea catechins, mainly (-)-epigallocatechin gallate, has shown numerous health promoting effects. However, various clinical studies demonstrated several issues associated with tea catechins which account for their poor systemic bioavailability. In order to improve pharmacological activity and bioavailability...
Absorption, metabolism, and excretion of (-)-epicatechin in humans: an evaluation of recent findings.
Alan Crozier
The American journal of clinical nutrition, 98(4), 861-862 (2013-08-30)
Seyung S Chung et al.
Anticancer research, 35(1), 39-46 (2015-01-01)
The cancer stem cell (CSC) model postulates the existence of a small proportion of cancer cells capable of sustaining tumor formation, self-renewal and differentiation. Signal Transducer and Activator of Transcription 3 (STAT3) signaling is known to be selectively activated in...
Anna Vogiatzoglou et al.
The British journal of nutrition, 111(8), 1463-1473 (2013-12-18)
Dietary interventions with flavan-3-ols have shown beneficial effects on vascular function. The translation of these findings into the context of the health of the general public requires detailed information on habitual dietary intake. However, only limited data are currently available...
Burcu Bekdeşer et al.
Journal of agricultural and food chemistry, 62(46), 11109-11115 (2014-11-05)
Hypochlorous acid (HOCl) is an important reactive oxygen species (ROS) and non-radical and is taking part in physiological processes concerned with the defense of the organism, but there has been limited information regarding its scavenging by polyphenols. This study was...
A Rinaldi et al.
Food chemistry, 164, 142-149 (2014-07-06)
The flavan-3-ol and proanthocyanidin composition of Aglianico seeds and skins were for the first time determined by HPLC-MS in comparison with the international grapes Merlot and Cabernet Sauvignon. Monomers [(+)-catechin C, (-)-epicatechin EC, (-)-epicatechin-3-O-gallate, ECG] and oligomers [B1, B2, B3...
V N Pavlov et al.
Urologiia (Moscow, Russia : 1999), (2)(2), 42-44 (2013-06-26)
The article presents a method of conservative treatment of men with I-II stage prostatic adenoma using a combination of doxazosin and indigal, which has antioxidant, antiproliferative and anti-inflammatory properties, that allowed improving urodynamic parameters and reducing the progression prostate adenoma...
Chee W How et al.
Biochimica et biophysica acta, 1838(5), 1215-1224 (2014-02-13)
Catechin flavonoids are the main components of green tea extracts which present broad potential physiological activities. Several of their biological activities seem to affect membrane-dependent cellular processes and it is known that some catechins interact with phospholipid membranes. In this...
Aleksander Salwiński et al.
Rapid communications in mass spectrometry : RCM, 28(18), 1957-1963 (2014-08-19)
Tyrosinase-coupled magnetic particles (EMPs) were used to demonstrate that resorcinol-containing tyrosinase inhibitors are oxidised by tyrosinase only in the presence of the enzyme's classic substrate. This shows the potential for the application of EMPs as a non-organic matrix for monitoring...
Jehan S Al-Amri et al.
Indian journal of experimental biology, 51(5), 357-362 (2013-07-05)
Degeneration of dopamine (DA)-containing neurons in the substantia nigra of the midbrain causes Parkinson's disease (PD). Although neuroinflammatory response of the brain has long been speculated to play a role in the pathogenesis of this neurological disorder, the mechanism is...
Juan Mielgo-Ayuso et al.
The British journal of nutrition, 111(7), 1263-1271 (2013-12-05)
The aim of the present study was to examine the effects of green tea epigallocatechin-3-gallate (EGCG) on changes in body composition, energy and substrate metabolism, cardiometabolic risk factors and liver function enzymes after an energy-restricted diet intervention in obese women....
S Misaka et al.
Clinical pharmacology and therapeutics, 95(4), 432-438 (2014-01-15)
This study aimed to evaluate the effects of green tea on the pharmacokinetics and pharmacodynamics of the β-blocker nadolol. Ten healthy volunteers received a single oral dose of 30 mg nadolol with green tea or water after repeated consumption of green...
Chun-Mao Yuan et al.
Journal of Asian natural products research, 15(6), 638-643 (2013-05-15)
Two new compounds, khayseneganin I (1) and 2α,3α,16β-trihydroxy-20-acetoxy-20(R)-pregnane (2), along with six known compounds, 2α,3α,20-trihydroxy-16β-acetoxy-20(R)-pregnane (3), 2α,3β-dihydroxypregnan-16-one-2β,19-hemiketal (4), (+)-catechin (5), ivorenolide A (6), luteolin-7-O-α-l-rhamnoside (7), and ( - )-5'-methoxy-isolariciresinol-2a-O-β-d-xylopyranoside (8), were isolated from the leaves and twigs of Khaya senegalensis. The structures...
Marie-Claude Denis et al.
Clinical science (London, England : 1979), 128(3), 197-212 (2014-07-30)
Cranberry fruit has been reported to have high antioxidant effectiveness that is potentially linked to its richness in diversified polyphenolic content. The aim of the present study was to determine the role of cranberry polyphenolic fractions in oxidative stress (OxS)...
Hyun-Ju Jang et al.
American journal of physiology. Endocrinology and metabolism, 305(12), E1444-E1451 (2013-10-24)
Insulin resistance, a hallmark of metabolic disorders, is a risk factor for diabetes and cardiovascular disease. Impairment of insulin responsiveness in vascular endothelium contributes to insulin resistance. The reciprocal relationship between insulin resistance and endothelial dysfunction augments the pathophysiology of...
Alejandro Cáceres-Mella et al.
Journal of agricultural and food chemistry, 62(29), 7255-7262 (2014-07-02)
The chemical and sensory effects of storing Sauvignon Blanc in colored bottles and exposing them to artificial light were examined. The colors of the bottles chosen were Dead Leaf Green, Antique Green, Amber, and Flint. The light was provided by...
Che C Colpitts et al.
Journal of virology, 88(14), 7806-7817 (2014-05-03)
Primary attachment to cellular glycans is a critical entry step for most human viruses. Some viruses, such as herpes simplex virus type 1 (HSV-1) and hepatitis C virus (HCV), bind to heparan sulfate, whereas others, such as influenza A virus...
C L Keen
Journal of the American College of Nutrition, 20(5 Suppl), 436S-439S (2001-10-18)
Cocoa and chocolate products have been delicacies for hundreds of years. Only recently have they been recognized as significant sources of phytochemicals with healthful effects. These foods are among the most concentrated sources of the procyanidin flavonoids, catechin and epicatechin....
Mi Ran Byun et al.
The Journal of biological chemistry, 289(14), 9926-9935 (2014-02-12)
Osteoporosis is a degenerative bone disease characterized by low bone mass and is caused by an imbalance between osteoblastic bone formation and osteoclastic bone resorption. It is known that the bioactive compounds present in green tea increase osteogenic activity and...
Milan S Geybels et al.
American journal of epidemiology, 177(12), 1388-1398 (2013-06-01)
Flavonoids are natural antioxidants found in various foods, and a major source is black tea. Some experimental evidence indicates that flavonoids could prevent prostate cancer. We investigated the associations between flavonoid intake, black tea consumption, and prostate cancer risk in...
Long-Ze Lin et al.
Journal of agricultural and food chemistry, 62(39), 9387-9400 (2014-07-18)
Oligomeric proanthocyanidins were successfully identified by UHPLC-PDA-HRMS(n) in a selection of plant-derived materials (jujube fruit, Fuji apple, fruit pericarps of litchi and mangosteen, dark chocolate, and grape seed and cranberry extracts). The identities of 247 proanthocyanidins were theoretically predicted by...
M Sałaga et al.
Naunyn-Schmiedeberg's archives of pharmacology, 387(11), 1069-1078 (2014-08-01)
Oenothera paradoxa (EP) preparations are commonly used in folk medicine to treat skin diseases, neuralgia, and gastrointestinal (GI) disorders. Several reports suggested that EP preparations exhibit potent anti-inflammatory and antioxidant activities both in vitro and in vivo. Here, we aimed...
Mario Lorenz
The American journal of clinical nutrition, 98(6 Suppl), 1642S-1650S (2013-11-01)
Green and black teas contain different biologically active polyphenolic compounds that might offer protection against a variety of human diseases. Although promising experimental and clinical data have shown protective effects, limited information is available on how these beneficial effects of...
Stéphane Bastianetto et al.
CNS neuroscience & therapeutics, 15(1), 76-83 (2009-02-21)
Various studies have reported on the neuroprotective effects of polyphenols, widely present in food, beverages, and natural products. For example, we have shown that resveratrol, a polyphenol enriched in red wine and other foods such as peanuts, protects hippocampal cells...
David A Camfield et al.
Nutrition reviews, 72(8), 507-522 (2014-06-21)
A systematic review and meta-analysis was conducted on 11 randomized placebo-controlled human studies of acute effects of tea constituents L-theanine and epigallocatechin gallate, administered alone or in combination with caffeine, on cognitive function and mood. The outcome measures of mood...
Ma G E González-Yáñez et al.
Evidence-based complementary and alternative medicine : eCAM, 2019, 7478152-7478152 (2020-01-18)
There is a trend to use medicinal plants for primary medical care or as dietary supplements; however, the safety of many of these plants has not been studied. The objective of this work was to determine the toxic effect of...
Hideyuki Ito et al.
The British journal of nutrition, 94(4), 500-509 (2005-10-04)
Dietary polyphenols are suggested to participate in the prevention of CVD and cancer. It is essential for epidemiological studies to be able to compare intake of the main dietary polyphenols in populations. The present paper describes a fast method suitable...
Rick Hursel et al.
The American journal of clinical nutrition, 98(6 Suppl), 1682S-1693S (2013-11-01)
Maintaining the level of daily energy expenditure during weight loss and weight maintenance is as important as maintaining satiety while decreasing energy intake. In this context, different catechin- and caffeine-rich teas (CCRTs), such as green, oolong, and white teas, as...
Hong-Bo Zhu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(9), 1386-1389 (2013-08-16)
To study the chemical constituents of Camellia sinensis var. assamica. The compounds were isolated by NKA Macroporous resin silica gel, Sephadex LH-20, RP-C18 column chromatographies and semi-preparative HPLC,and their structures were elucidated by physicochemical properties and spectral analysis. Thirteen compounds...
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