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Maria João Rocha et al.
Journal of water and health, 11(2), 281-296 (2013-05-28)
A gas chromatography with mass spectrometric detection (GC-MS) method was developed and optimized for the determination of 17 endocrine disrupting compounds (EDCs) in coastal water samples. The evaluated EDCs were from different origins and included estrogens, bisphenol A, alkylphenolethoxylates, alkylphenols...
Chun Shi et al.
Biochimica et biophysica acta, 1830(3), 2538-2544 (2012-12-26)
Brain lipid peroxidation has long been considered a potential therapeutic target for Alzheimer's disease (AD). beta-sitosterol (BS), a plant sterol that is prevalent in plant plasma membrane, has been suggested to have antioxidant activity. Previous studies have demonstrated that dietary...
Simone P Barbosa et al.
Life sciences, 92(14-16), 845-851 (2013-03-20)
High-risk subjects with elevated C-reactive protein (CRP) are at high risk for cardiovascular events and frequently require potent statins or combined lipid-lowering therapy to achieve lipid targets and decrease inflammation. Our study aimed at evaluating the effects of three lipid-modifying...
Flora Pensec et al.
Journal of agricultural and food chemistry, 62(32), 7998-8007 (2014-07-25)
Triterpenoids present in grape cuticular waxes are of interest due to their potential role in protection against biotic stresses, their impact on the mechanical toughness of the fruit surface, and the potential industrial application of these biologically active compounds from...
Youngki Park et al.
Nutrition research (New York, N.Y.), 33(2), 154-161 (2013-02-13)
Dietary consumption of phytosterols and certain fatty acids has been shown to reduce cholesterol absorption and plasma cholesterol concentrations. However, it has not been fully elucidated whether phytosterols or fatty acids can alter the expression of cholesterol transporters by functioning...
Ju-ying Zou et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(5), 724-725 (2012-12-12)
To study the chemical constituents of Pileostegia viburnoides var. glabrescens. The compounds were isolated and purified by various techniques. Their structures were determined by physicochemical properties and spectral analysis. Five compounds were isolated and identified as friedelin (1), beta-sitosterol (2)...
Geovanni Espinosa
Current opinion in urology, 23(1), 38-41 (2012-12-04)
Nutrition seems to modify the pathogenesis of benign prostatic hyperplasia (BPH) effect symptomology in men suffering from lower urinary tract symptoms (LUTS). Although there are numerous pharmaceuticals and procedures for these conditions, nutrition may improve outcomes as a primary approach...
Tian-Shan Wang et al.
Natural product communications, 8(10), 1427-1429 (2013-12-21)
Two new compounds, (+)-rumphiin (3) and polyalthurea (7), together with seven known ones, 3,4,5-trimethoxy benzoic acid (1), (-)-seselinone (2), cannabisin D (4), allantoin (5), oxostephanine (6) and a mixture of beta-sitosterol (8) and stigmasterol (9) were isolated from the stems...
Ashutosh Singh
Food chemistry, 137(1-4), 62-67 (2012-12-04)
The antioxidative effect of sitosterol at 1, 2 and 5% levels, in triolein, refined canola, high oleic sunflower and flaxseed oils, continuously heated for a period of up to 72 h at frying temperature of 180 °C, was studied. High...
Günther Silbernagel et al.
Current opinion in lipidology, 24(1), 12-17 (2012-11-21)
Plant sterols as ingredients to functional foods are recommended for lowering LDL cholesterol. However, there is an ongoing discussion whether the use of plant sterols is safe. Genetic analyses showed that common variants of the ATP binding cassette transporter G8...
Na-Ra Han et al.
Experimental biology and medicine (Maywood, N.J.), 239(4), 454-464 (2014-02-11)
The compound β-sitosterol (BS) is one of the most common forms of phytosterols and has anti-cancer, anti-oxidant, anti-bacterial, and anti-inflammatory effects. However, the effect of BS on atopic dermatitis (AD) has not been elucidated. Therefore, we investigated whether BS would...
Keiko Miyazaki et al.
Journal of vascular surgery, 48(4), 986-993 (2008-07-01)
The patency of prosthetic grafts is partly limited by incomplete endothelial cell coverage and development of anastomotic intimal hyperplasia. The goal of this study was to determine the effect of elevated cholesterol on prosthetic graft healing and the ability of...
I Lacatusu et al.
Nanotechnology, 23(45), 455702-455702 (2012-10-16)
In this work, new stable and efficiently bio-active lipid nanocarriers (NLCs) with antioxidant properties have been developed for the transport of active ingredients in food. The novel NLCs loaded with β-sitosterol/β-sitosterol and green tea extract (GTE) and prepared by a...
Graziana Lupattelli et al.
Journal of clinical lipidology, 7(2), 147-152 (2013-02-19)
To investigate the influence of the silent mutation c.816C > G (L272) of Niemann-Pick C1-like 1 (NPC1L1) and of apolipoprotein (APO) E alleles on cholesterol absorption markers, sitosterol and campesterol, in 87 patients with primary hyperlipidemias. In all subjects genotyped...
Olga Renner et al.
BMC gastroenterology, 13, 30-30 (2013-02-15)
Gallstone disease is associated with p.D19H of ABCG8 as well as alterations of cholesterol and bile acid metabolism. However, molecular mechanisms have not been fully elucidated. It is important to understand the link between the sterol transporters ABCG5/8 and NPC1L1...
Rafael Liz et al.
The Journal of pharmacy and pharmacology, 65(1), 115-122 (2012-12-12)
To evaluate the effect of β-sitosterol on ⁴⁵Ca²⁺ uptake in activated murine neutrophils, and upon myeloperoxidase and adenosine deaminase activity, and interleukin-1β (IL-1β) and tumour necrosis factor-α (TNF-α) levels, in carrageenan-induced inflammation in the mouse air pouch model. Dried Esenbeckia...
Natalia Toro-Funes et al.
Journal of agricultural and food chemistry, 62(39), 9539-9543 (2014-09-05)
Ultra-high-pressure homogenization (UHPH) is an emerging technology based on the dynamic application of high pressure to obtain safe and high-quality liquid foods. The effect of six UHPH treatments at 200 and 300 MPa with different inlet temperatures (T(in)) (55, 65...
Ikarastika Rahayu Abdul-Wahab et al.
Journal of ethnopharmacology, 144(3), 741-746 (2012-10-27)
Local communities in Malaysia consume Pereskia bleo Kunth. (Cactaceae) leaves as raw vegetables or as a concoction and drink as a tea to treat diabetes, hypertension, rheumatism, cancer-related diseases, inflammation, gastric pain, ulcers, and for revitalizing the body. To evaluate...
Marcelo Abrahão Strauch et al.
Journal of ethnopharmacology, 145(1), 50-58 (2012-11-06)
Although serotherapy against snakebite has been discovered more than one hundred years ago, antivenom is not available all over Brazil. The use of plants from folk medicine is common mainly in the Brazilian Amazon area. One of these plants is...
Z Ovesná et al.
Neoplasma, 51(6), 407-414 (2005-01-11)
Substantial attention has been given to primary cancer prevention in daily life. Dietary factors are through to contribute to as much as one-third of the factors influencing the development of cancer. Ones of the components of a plant-based diet are...
Xing-Bo Li et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(10), 1543-1547 (2013-08-21)
Sixteen compounds were isolated from Conioselinum vaginatum by silica column chromatography over silica gel and Sephadex LH-20, as well as recrystallization. On the basis of their physical and chemical properties and spectral data, their structures were identified as ligustilide (1)...
Laurian Vlase et al.
Molecules (Basel, Switzerland), 18(1), 114-127 (2013-01-25)
The aim of this work was to study the chemical composition of Allium obliquum L., A. senescens L. subsp. montanum (Fries) Holub, and A. schoenoprasum L. subsp. schoenoprasum. Sulphur-containing compounds analysis was performed by an LC-MS method, the identification and...
Yang Zou et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(7), 1095-1097 (2012-12-21)
To study the chemical constituents from Astilbe myriantha. The constituents were isolated and purified by column chromatography methods and recrystallization. Their structures were identified on the basis of physiochemical properties and special analysis. Ten compounds were isolated from 95% ethanol...
Awanish Kumar Pandey et al.
Journal of basic and clinical physiology and pharmacology, 24(1), 35-39 (2012-11-28)
The use of medicinal plants has turned out to be an alternative method for the treatment of diseases, such as diabetes mellitus. The recommendation of the World Health Organization Committee on Diabetes encouraging research on hypoglycemic agents of plant origin...
Rgia A Othman et al.
The Journal of pediatrics, 166(1), 125-131 (2014-12-03)
To assess if ezetimibe (EZE), a sterol-absorption inhibitor, improves platelet (PLT) count and size relative to its effect on plasma plant sterol (PS) in patients with sitosterolemia (STSL). Patients with STSL (5 males, 3 females, 16-56 years of age) receiving...
Fan-Jhen Dai et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 384-391 (2013-01-05)
Obesity is associated with increased systemic and airway oxidative stress, which may result from a combination of adipokine imbalance and antioxidant defenses reduction. Obesity-mediated oxidative stress plays an important role in the pathogenesis of dyslipidemia, vascular disease, and nonalcoholic hepatic...
M A Nurseitova et al.
Journal of dairy science, 102(9), 7723-7733 (2019-07-01)
Milk fat adulteration is a common issue in Central Asia. To assess the current situation in the commercial milk market, 17 milk samples were checked for fatty acid (FA) and sterol profiles to detect potential adulteration using multivariate analysis. Analysis...
Chao Yang et al.
Cardiovascular research, 97(3), 520-532 (2012-12-20)
β-Sitosterol has become a popular cholesterol-lowering functional food product worldwide. β-Sitosterol can be oxidized to β-sitosterol oxidation products (SOPs) during food processing. Little is known about the impact of SOPs and β-sitosterol on the functionality of arteries. This study investigated...
T J Wilt et al.
BJU international, 83(9), 976-983 (1999-06-15)
To conduct a systematic review of the evidence for the efficacy of beta-sitosterol in men with symptomatic benign prostatic hyperplasia (BPH). Studies were identified through Medlinetrade mark (1966-98), EMBASEtrade mark, Phytodok, the Cochrane Library, bibliographies of identified trials and review...
Mira Rosenblat et al.
Atherosclerosis, 226(1), 110-117 (2012-11-13)
To assess the anti-atherogenic effects on macrophage cholesterol biosynthesis rate, and on cellular oxidative stress by the combination of simvastatin with a potent polyphenolic antioxidant (punicalagin), or with a phytosterol (β-sitosterol), or with pomegranate juice (POM, that contains both of...
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