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Federica Ianni et al.
Journal of chromatography. A, 1363, 101-108 (2014-04-15)
While aliphatic 2-hydroxyalkanoic acids have been more or less successfully enantioseparated with various chiral stationary phases by HPLC and GC, analogous applications on underivatized aliphatic 3-hydroxyalkanoic acids are completely absent in the scientific literature. With the aim of closing this
K V Dmitruk et al.
TSitologiia i genetika, 47(6), 3-21 (2014-01-21)
Until recently, the methylotrophic yeast was not considered as a potential producer of biofuels, particularly of ethanol from lignocellulosic hydrolysates. The first work published 10 years ago reveals the ability of thermotolerant methylotrophic yeast Hansenula polymorpha to ferment xylose--one of
Sinisa Vidovic et al.
Antimicrobial agents and chemotherapy, 59(6), 3317-3328 (2015-03-25)
In this study, we tested the antimicrobial activity of three metal nanoparticles (NPs), ZnO, MgO, and CaO NPs, against Salmonella enterica serovar Enteritidis in liquid medium and on solid surfaces. Out of the three tested metal NPs, ZnO NPs exhibited
Elżbieta Sikora et al.
Colloids and surfaces. B, Biointerfaces, 126, 541-545 (2015-01-27)
The skin permeation of forskolin, a diterpene isolated from Coleus forsholii, was studied using oil in water (O/W) emulsions as delivery formulations and also an oil solution for comparative purposes. Two forskolin-loaded emulsions of water/Brij 72:Symperonic A7/Miglyol 812:Isohexadecane, at 0.075
Christina O'Rourke et al.
Annals of botany, 116(2), 225-236 (2015-06-27)
During evolution, plants have acquired and/or lost diverse sugar residues as cell-wall constituents. Of particular interest are primordial cell-wall features that existed, and in some cases abruptly changed, during the momentous step whereby land-plants arose from charophytic algal ancestors. Polysaccharides
L Marcellin et al.
Human reproduction (Oxford, England), 30(2), 392-405 (2014-11-30)
Are the fetal membranes of women affected with endometriosis similar to those from disease-free women? Decidua of women with endometriosis is able to generate endometriotic-like lesions in contact with the fetal membranes. Eutopic endometrium of women affected with endometriosis presents
Cássia Valério Romanini et al.
Journal of neuroscience research, 93(8), 1240-1249 (2015-02-24)
4-Hydroxy-3-methoxy-acetophenone (apocynin) is a naturally occurring methoxy-substitute catechol that is isolated from the roots of Apocynin cannabinum (Canadian hemp) and Picrorhiza kurroa (Scrophulariaceae). It has been previously shown to have antioxidant and neuroprotective properties in several models of neurodegenerative disease
H Hu et al.
The Journal of hospital infection, 91(1), 35-44 (2015-07-19)
Hospital-associated infections cause considerable morbidity and mortality, and are expensive to treat. Organisms causing these infections can be sourced from the inanimate environment around a patient. Could the difficulty in eradicating these organisms from the environment be because they reside
Liwei Dong et al.
International journal of molecular sciences, 16(7), 14655-14668 (2015-07-02)
Echinacoside is a natural compound with potent reactive oxygen species (ROS)-scavenging and anti-oxidative bioactivities, which protect cells from oxidative damages. As cancer cells are often under intense oxidative stress, we therefore tested if Echinacoside treatment would promote cancer development. Surprisingly
Cristina Potrich et al.
Lab on a chip, 14(20), 4067-4075 (2014-09-02)
There is an increasing interest in circulating microRNAs (miRNAs) as potential minimally invasive diagnostic biomarkers in oncology. Considerable efforts are being made in the development of lab-on-a-chip devices for biomedical applications to purify and detect miRNAs from biological fluids. Here
Eleni Stamellou et al.
PloS one, 9(6), e99298-e99298 (2014-06-14)
N-acyl dopamines (NADD) are gaining attention in the field of inflammatory and neurological disorders. Due to their hydrophobicity, NADD may have access to the endoplasmic reticulum (ER). We therefore investigated if NADD induce the unfolded protein response (UPR) and if
Veronica Bianchi et al.
Reproductive biology and endocrinology : RB&E, 12, 110-110 (2014-11-26)
Human mature oocytes are very susceptible to cryodamage. Several reports demonstrated that vitrification might preserve oocyte better than slow freezing. However, this is still controversial. Thus, larger clinical, biological and experimental trials to confirm this concept are necessary. The aim
María Teresa Sánchez-Fito et al.
Biopreservation and biobanking, 13(4), 287-295 (2015-08-19)
It has been known for decades that many cytokines, such as IL-2, IL-6, and IL-12, bind to heparin. Even though some enzyme-linked immunosorbent assays (ELISA) use antibody-recognizing epitopes not affected by this binding, ELISA manufacturers often warn that heparinized plasma
Hisako Hikiji et al.
Journal of materials science. Materials in medicine, 25(6), 1531-1538 (2014-02-28)
Rapid and efficient animal models are needed for evaluating the effectiveness of many new candidate bone regenerative materials. We developed an in vivo model screening for calvarial bone regeneration in lipopolysaccharide (LPS)-treated mice, in which materials were overlaid on the
Andrea M P Romani
Alcohol (Fayetteville, N.Y.), 49(3), 265-273 (2015-03-25)
Alcoholic cardiomyopathy represents a major clinical complication in chronic alcoholics. Previous studies from our laboratory indicate that acute and chronic exposure of liver cells to ethanol results in a major loss of cellular Mg(2+) as a result of alcohol oxidation.
Tao Liu et al.
Neuroscience letters, 584, 390-394 (2014-12-03)
Neuropeptides such as neurotensin (NT), and enkephalin (ENK) in the medullary dorsal horn (MDH) are involved in excitatory synaptic transmission to modulate nociceptive information. However, morphological evidence indicating that NT or ENK coexists with glutamate in the MDH is still
Shelly R H Pecorella et al.
American journal of physiology. Lung cellular and molecular physiology, 309(8), L857-L871 (2015-07-19)
The heme oxygenase-1 (HO-1)/carbon monoxide (CO) system induces mitochondrial biogenesis, but its biological impact in human skeletal muscle is uncertain. The enzyme system generates CO, which stimulates mitochondrial proliferation in normal muscle. Here we examined whether CO breathing can be
Ke Tang et al.
Journal of the science of food and agriculture, 94(12), 2472-2481 (2014-01-22)
[corrected] Seven anthocyanin monomers of Yan 73 grape were separated using preparative HPLC and identified by UPLC-ESI-MS/MS. The stabilities of the seven isolated anthocyanins to light, temperature and pH were also investigated. Seven anthocyanin monomers were successfully isolated with an
Scott J Davis et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(29), 9562-9573 (2014-07-18)
Alcohol directly modulates the BK potassium channel to alter behaviors in species ranging from invertebrates to humans. In the nematode Caenorhabditis elegans, mutations that eliminate the BK channel, SLO-1, convey dramatic resistance to intoxication by ethanol. We hypothesized that certain
Haoming Li et al.
In vitro cellular & developmental biology. Animal, 51(4), 329-335 (2014-12-06)
LIM-homeobox genes play a pivotal function in tissue patterning and differentiation, Lhx8 is a member of LIM-homeobox gene family, and it is selectively expressed in embryonic basal forebrain and is a key factor for the determination of cholinergic cells fate.
Nagananda Gurudev et al.
Biology open, 3(5), 332-341 (2014-04-08)
The apical surface of epithelial cells is often highly specialised to fulfil cell type-specific functions. Many epithelial cells expand their apical surface by forming microvilli, actin-based, finger-like membrane protrusions. The apical surface of Drosophila photoreceptor cells (PRCs) forms tightly packed
Vasudevan Achuthan et al.
BMC biochemistry, 16, 12-12 (2015-05-03)
Fidelity of DNA polymerases can be influenced by cation co-factors. Physiologically, Mg(2+) is used as a co-factor by HIV reverse transcriptase (RT) to perform catalysis; however, alternative cations including Mn(2+), Co(2+), and Zn(2+) can also support catalysis. Although Zn(2+) supports
Oliver Wahl et al.
Journal of pharmaceutical and biomedical analysis, 114, 254-264 (2015-06-21)
The modern bisphosphonate drug ibandronate sodium, a challenging candidate for impurity profiling, was analyzed using high performance liquid chromatography (HPLC) combined with corona charged aerosol detection (CAD). Separation was achieved on a mixed mode column combining hydrophobic C18 and strong
Yingqi Cai et al.
The Plant cell, 27(9), 2616-2636 (2015-09-13)
The lipodystrophy protein SEIPIN is important for lipid droplet (LD) biogenesis in human and yeast cells. In contrast with the single SEIPIN genes in humans and yeast, there are three SEIPIN homologs in Arabidopsis thaliana, designated SEIPIN1, SEIPIN2, and SEIPIN3.
Suguna P Narayan et al.
Small (Weinheim an der Bergstrasse, Germany), 11(33), 4173-4182 (2015-06-23)
The sequence-dependent cellular uptake of spherical nucleic acid nanoparticle conjugates (SNAs) is investigated. This process occurs by interaction with class A scavenger receptors (SR-A) and caveolae-mediated endocytosis. It is known that linear poly(guanine) (poly G) is a natural ligand for
Tanmay Bera et al.
ACS applied materials & interfaces, 7(26), 14528-14535 (2015-06-16)
We report that liquid crystal elastomers (LCEs), often portrayed as artificial muscles, serve as scaffolds for skeletal muscle cell. A simultaneous microemulsion photopolymerization and cross-linking results in nematic LCE microspheres 10-30 μm in diameter that when conjoined form a LCE
Ran Du et al.
PloS one, 9(4), e94480-e94480 (2014-04-17)
The rising demand for bioethanol, the most common alternative to petroleum-derived fuel used worldwide, has encouraged a feedstock shift to non-food crops to reduce the competition for resources between food and energy production. Sweet sorghum has become one of the
G P Lv et al.
Journal of pharmaceutical and biomedical analysis, 109, 105-111 (2015-03-15)
It was shown that different extracts had significant differences in the toxicity of Polygonum multiflorum. In this study, the effect of sample preparation on components and liver toxicity of different extracts from P. multiflorum were determined. Hepatoxic components were discovered
Takahiko Toyonaga et al.
PloS one, 10(8), e0135552-e0135552 (2015-08-15)
Osteopontin (OPN) is a multifunctional protein expressed in a variety of tissues and cells. Recent studies revealed increased OPN expression in the inflamed intestinal tissues of patients with inflammatory bowel disease (IBD). The role of OPN in the pathophysiology of
Zhe Wang et al.
ACS nano, 9(7), 6683-6695 (2015-05-29)
Recent advances in neural stem cell (NSC) transplantation have led to an inspiring progress in alleviating central nervous system (CNS) damages and restoring brain functions from diseases or injuries. One challenge of NSC transplantation is directed differentiation of transplanted NSCs
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