Victoria Díaz-Tomé et al.
Journal of pharmaceutical sciences, 107(5), 1342-1351 (2018-01-07)
Econazole is a feasible alternative treatment in the management of fungal keratitis. Nevertheless, its low water solubility is considered the main limitation to the incorporation into ophthalmic formulations. In this work, econazole nitrate is solubilized by using cyclodextrins to achieve