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Exibindo 1-30 of 128 resultados para "75-52-5" no prazo de Papéis
National Toxicology Program technical report series, (528)(528), 1-190 (2005-12-20)
The NTP chose to initiate studies in fish as an exploration of alternate or additional models for examining chemical toxicity and carcinogenicity. The use of small fish species in carcinogenicity testing offered potential advantages as a bioassay test system, including
Y B Han et al.
Molecular reproduction and development, 74(9), 1132-1140 (2007-03-08)
Expression of T-complex testis expressed 5 (Tctex5), an orthologue of protein phosphatase-1 inhibitor-3 (PPP1R11), was enhanced in mouse testis and was also expressed in epididymis and spermatozoa. There were three transcripts of Tctex5 including one brain specific and two common
J H Martin et al.
Cancer letters, 144(1), 65-74 (1999-09-30)
We have recently reported the presence of inducible nitric oxide synthase (iNOS) in the human breast cancer cell line ZR-75-1. The purpose of the present study was to examine differences in expression of endothelial (eNOS) and inducible nitric oxide synthase
Jin Wang et al.
Medical oncology (Northwood, London, England), 27(2), 219-223 (2009-03-18)
Expression of the Raf kinase inhibitor protein (RKIP), a metastasis suppressor, is high in normal tissues, low in primary cancers, and lowest or absent in metastatic cancers. Here, we studied the expression of RKIP in nonneoplastic gastric tissue and gastric
N Inoue et al.
Clinical and experimental immunology, 163(3), 318-323 (2011-01-18)
To clarify the association of genetic producibility of interleukin (IL)-5, IL-6 and IL-13, which are secreted by T helper type 2 (Th2), with the development and prognosis of autoimmune thyroid disease (AITD), we genotyped IL5-746C/T, IL6-572C/G and IL13-1112C/T polymorphisms, which
Skander Mulder et al.
Translational research : the journal of laboratory and clinical medicine, 222, 17-27 (2020-05-22)
The mineralocorticoid receptor antagonist spironolactone significantly reduces albuminuria in subjects with diabetic kidney disease, albeit with a large variability between individuals. Identifying novel biomarkers that predict response to therapy may help to tailor spironolactone therapy. We aimed to identify a
B A Diwan et al.
Cancer research, 48(9), 2492-2497 (1988-05-01)
Male F344/NCr rats, 6 wk old, were fed 500 ppm of phenobarbital (PB) or equimolar doses of either 5-ethyl-5-phenylhydantoin (EPH) or 5,5-diethylhydantoin (EEH) in diet for 2 wk and hepatic cytochrome P-450-mediated alkoxyresorufin O-dealkylase and aminopyrine N-demethylase activities were determined.
N H Kim et al.
Journal of applied microbiology, 119(1), 139-148 (2015-03-31)
To develop a mild blanching method with calcium salts to ensure microbiological safety and quality of fresh-cut spinach. The antimicrobial efficacy of eight calcium salts was evaluated on Escherichia coli O157:H7 at 45-65°C and calcium hydroxide (Ca(OH)2 ) showed the
Andrew Blauvelt et al.
Lancet (London, England), 389(10086), 2287-2303 (2017-05-10)
Dupilumab (an anti-interleukin-4-receptor-α monoclonal antibody) blocks signalling of interleukin 4 and interleukin 13, type 2/Th2 cytokines implicated in numerous allergic diseases ranging from asthma to atopic dermatitis. Previous 16-week monotherapy studies showed that dupilumab substantially improved signs and symptoms of
Megha Suri et al.
Pediatric research, 76(4), 370-377 (2014-07-06)
Endogenous glucagon-like peptide-2 (GLP-2) levels and intestinal adaptation are reduced in distal-intestinal resection animal models of short bowel syndrome (SBS) that lack remnant ileum. We hypothesized that exogenous GLP-2 would improve intestinal adaptation in a distal-intestinal resection neonatal piglet model
P J Boogaard et al.
Environmental health perspectives, 102 Suppl 6, 23-25 (1994-10-01)
In two studies, involving 75 and 72 workers, potential exposure to 3-chloro-4-fluoroaniline (CFA) was biologically monitored by determination of its main urinary metabolite 2-amino-4-chloro-5-fluorophenol sulfate (CFA-S). As this method only allows the detection of recent exposure, analysis of CFA adducts
K Szepeshazi et al.
International journal of cancer, 49(2), 260-266 (1991-09-09)
Ductal pancreatic cancers were induced with N-nitrosobis(2-oxopropyl)amine (BOP) in female Syrian golden hamsters. The animals were then treated for 2 months with 5-fluorouracil (5-FU) and with sustained delivery systems of the LH-RH agonist D-Trp-6-LH-RH antagonist (Ac-D-Nal(2)'-D-Phe(4Cl)2-D-Pal(3)3-D-Cit6,D-Ala10)LH- RH(SB-75) and somatostatin analog
Alicia B Minns et al.
The American journal of emergency medicine, 31(6), 964-966 (2013-04-23)
This retrospective study aims to review California Poison Control System data to qualitatively describe reported methyl acetate (MA) exposures and determine if a metabolic acidosis develops. We queried the Poison Control System data between January 1997 and December 1, 2010.
Caroline Kannengiesser et al.
Human mutation, 29(9), E132-E149 (2008-06-12)
Chronic granulomatous disease (CGD) results from constitutional inactivating mutations in the CYBB, NCF1, CYBA or NCF2 genes that encode subunits of phagocyte NADPH oxidase. We report the findings of molecular analysis of 80 kindred. In 75 unrelated male and 5
A A Jungbluth et al.
The American journal of surgical pathology, 22(5), 595-602 (1998-05-20)
Melan-A is a previously defined, melanocyte differentiation antigen, and an anti-Melan-A murine monoclonal antibody, A103, was recently developed by our group. In this study, we evaluated A103 immunoreactivity on formalin-fixed, paraffin-embedded tissues, exploring the potential of A103 in the diagnosis
B A Carr et al.
Xenobiotica; the fate of foreign compounds in biological systems, 28(10), 949-956 (1998-12-16)
1. Changes in the major hepatic drug-metabolizing enzymes by compounds identified as atypical inducers (multienzyme response but devoid of cytochrome P450-inducing ability) in rat were investigated in mouse. Animals were treated with 1,7-phenanthroline, 2,2'-dipyridyl, 7,8-benzoquinoline and oltipraz at 75 and
Meltem Isikgoz Tasbakan et al.
International journal of antimicrobial agents, 40(6), 554-556 (2012-10-16)
The aim of this study was to evaluate the effect of nitrofurantoin (NFT) in the treatment of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli-related lower urinary tract infection (LUTI). The hospital records of all patients aged >18 years with dysuria or problems
Jingcui Yu et al.
Molecules and cells, 32(1), 47-55 (2011-05-03)
Previously, we identified 3 overlapping regions showing loss of heterozygosity (LOH, R(1)-R(3) from 11 to 30 cM) on chromosome 17 in 45 primary gastric cancers (GCs). The data indicated the presence of tumor suppressor genes (TSGs) on chromosome 17 involved
Muhammad Yasir et al.
Scientific reports, 9(1), 7063-7063 (2019-05-10)
Melimine and Mel4 are chimeric cationic peptides with broad-spectrum antimicrobial activity. They have been shown to be highly biocompatible in animal models and human clinical trials. The current study examined the mechanism of action of these two antimicrobial peptides against
Monika Korabiowska et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 17(12), 1539-1544 (2004-07-17)
Adenomatous polyposis coli gene (APC) defects have been demonstrated for the first time in familial adenomatous polyposis. Recent reports indicate that the APC gene is an intermediary between cell adhesion molecules and the cytoskeleton and that it may function as
Yo Sasaki et al.
Cancer, 94(6), 1777-1786 (2002-03-29)
Hepatocellular carcinoma (HCC) is a vascular-rich tumor. The tumor vessels in HCC were demonstrated to have alpha-smooth muscle actin positive smooth muscle cells (SMCs). However, it is unclear whether the SMCs in the wall of the tumor vessels are differentiated
Ralf R Regeer et al.
DNA and cell biology, 22(2), 107-117 (2003-04-26)
Sulfate plays an essential role during growth, development, bone/cartilage formation, and cellular metabolism. In this study, we have isolated the human sulfate anion transporter cDNA (hsat-1; SCL26A1) and gene (SAT1), determined its protein function in Xenopus oocytes and characterized SAT1
M G Martín et al.
The American journal of physiology, 275(4 Pt 1), G778-G788 (1998-10-02)
The regulatory elements that control basal and activated transcriptional expression of the polymeric IgA receptor gene (pIgR) have not been defined. In this study, we performed functional analysis of the murine pIgR 5'-upstream region. Transient transfection studies identified the gene's
H Takahashi et al.
The Journal of biological chemistry, 263(29), 14739-14747 (1988-10-15)
The gene for human neutrophil elastase (NE), a powerful serine protease carried by blood neutrophils and capable of destroying most connective tissue proteins, was cloned from a genomic DNA library of a normal individual. The NE gene consists of 5
V G Curtui et al.
Food additives and contaminants, 18(8), 730-738 (2001-07-27)
Blood serum, kidney, liver and muscle sample per animal were collected from slaughtered pigs (n = 52). The samples were analysed for ochratoxin A (OTA) and B (OTB) by HPLC methods. Zearalenone (ZEA) in serum was analysed by enzyme immunoassay.
Amish A Naik et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 24(2), 251-264 (2008-10-14)
The cellular and molecular events responsible for reduced fracture healing with aging are unknown. Cyclooxygenase 2 (COX-2), the inducible regulator of prostaglandin E(2) (PGE(2)) synthesis, is critical for normal bone repair. A femoral fracture repair model was used in mice
Elin Kindberg et al.
The Journal of infectious diseases, 203(4), 523-528 (2011-01-11)
Tick-borne encephalitis virus (TBEV) infections may be asymptomatic or cause severe symptoms in the central nervous system. A mutation in the chemokine receptor 5 gene has been associated with increased risk of TBE but explains only a limited number of
Xianzong Xie et al.
IEEE transactions on bio-medical engineering, 60(10), 2943-2951 (2013-06-12)
We present an encapsulation scheme that combines atomic layer deposited (ALD) Al₂O₃ and Parylene C for the encapsulation of implantable devices. The encapsulation performances of combining alumina and Parylene C was compared to individual layers of Parylene C or alumina
H Uchiyama et al.
Blood, 80(9), 2306-2314 (1992-11-01)
In multiple myeloma, malignant plasma cells are localized in marrow and rarely circulate in peripheral blood. To investigate the role of adhesion proteins in this process, we determined the expression and function of adhesion molecules on cell lines derived from
Arfana Mallah et al.
TheScientificWorldJournal, 2012, 743407-743407 (2012-06-01)
Micellar electrokinetic chromatography (MEKC) was examined for the separation and determination of Mo(VI), Cr(VI), Ni(II), Pd(II), and Co(III) as diethyl dithiocarbamate (DDTC) chelates. The separation was achieved from fused silica capillary (52 cm × 75 μm id) with effective length
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