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Taichi Inui et al.
Applied and environmental microbiology, 81(16), 5471-5476 (2015-06-07)
Carbohydrate availability shifts when bacteria attach to a surface and form biofilm. When salivary planktonic bacteria form an oral biofilm, a variety of polysaccharides and glycoproteins are the primary carbon sources; however, simple sugar availabilities are limited due to low
Amun Makani et al.
The Journal of arthroplasty, 29(4), 827-830 (2013-09-28)
The purpose of this study was to evaluate the outcome of femoral component revisions using a long tapered HA coated femoral revision stem. Between 2001 and 2008, 55 femoral component revisions were performed using this stem. Forty-one patients were available
E Buraka et al.
Chemico-biological interactions, 220, 200-207 (2014-07-13)
The ability to intercalate between DNA strands determines the cytotoxic activity of numerous anticancer drugs. Strikingly, intercalating activity was also reported for some compounds considered to be antimutagenic. The aim of this study was to determine the mode of interaction
Lu-Ning Wang et al.
Journal of nanoscience and nanotechnology, 13(8), 5316-5326 (2013-07-26)
Electrochemically anodized TiO2 nanotubular arrays can provide large surface areas for biological species attachment. In order to further enhance the biocompatibility of Ti medical implants, we deposited a pre-synthesized hydroxyapatite inside and on the nanotubular arrays, and examined the biocompatibility
Radosław Olkowski et al.
Journal of materials science. Materials in medicine, 26(12), 270-270 (2015-10-30)
Calcium phosphate cements (CPC) are valuable bone fillers. Recently they have been also considered as the basis for drug-, growth factors- or cells-delivery systems. Broad possibilities to manipulate CPC composition provide a unique opportunity to obtain materials with a wide
D Nuttall et al.
The bone & joint journal, 96-B(8), 1077-1081 (2014-08-03)
Resurfacing of the humeral head is commonly used within the UK to treat osteoarthritis (OA) of the shoulder. We present the results of a small prospective randomised study of this procedure using the Global CAP prosthesis with two different coatings
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute
Sang-Woon Lee et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(1), 53-60 (2013-12-18)
The objective of this study was to compare peri-implant bone formation among uncoated (UC), hydroxyapatite (HA), collagen plus HA (CH), and collagen, HA, plus bone morphogenetic protein-2 (BMP-2) implant groups. Implants in the UC group had acid-etched surfaces. The surface
Muriel Babey et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(6), 1064-1076 (2014-12-17)
The primary goal of this study was to determine whether the IGF1R in mature osteoblasts and osteocytes was required for the catabolic actions of continuous parathyroid hormone (cPTH). Igf1r was deleted from male and female FVN/B mice by breeding with
Yoshitaka Ogita et al.
The Journal of biological chemistry, 290(33), 20245-20256 (2015-07-08)
The Ras family of small GTPases function in a wide variety of biological processes as "molecular switches" by cycling between inactive GDP-bound and active GTP-bound forms. Di-Ras1 and Di-Ras2 were originally identified as small GTPases forming a distinct subgroup of
Shin-Woo Ha et al.
Biomaterials, 65, 32-42 (2015-07-05)
Hydroxyapatite (HA) is the primary structural component of the skeleton and dentition. Under biological conditions, HA does not occur spontaneously and therefore must be actively synthesized by mineralizing cells such as osteoblasts. The mechanism(s) by which HA is actively synthesized
Francisco Miguel Cardoso et al.
Journal of virology, 88(15), 8278-8296 (2014-05-16)
Influenza virus neuraminidase (NA) is an interesting target of small-molecule antiviral drugs. We isolated a set of H5N1 NA-specific single-domain antibodies (N1-VHHm) and evaluated their in vitro and in vivo antiviral potential. Two of them inhibited the NA activity and
Constantin Landes et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(7), 1328-1338 (2014-04-08)
To evaluate the internal fixation of malar and midfacial fractures, long-term results, and biocompatibility of osteoconductive internal fixation devices composed of a forged composite of unsintered hydroxyapatite and poly-L-lactide (F-u-HA/PLLA). From January 2006 to June 2010, 29 patients (24 males
Takamasa Shimizu et al.
Cryobiology, 66(3), 326-332 (2013-04-09)
Cryopreservation of tissue engineered bone (TEB), whilst maintaining its osteogenic ability, is imperative for large-scale clinical application. We previously reported a novel cell transplantation method, in which bone-marrow-derived mesenchymal stem cells (BMSCs) were cultured to confluence and differentiated down the
Y Lei et al.
Journal of dental research, 93(12), 1264-1269 (2014-09-25)
Dental professionals are seeing a growing population of patients with visible signs of dental erosion. The approach currently being used to address the problem typically leverages the enamel protection benefits of fluoride. In this report, an alternative new block copolymer
Fangfang Sun et al.
Journal of biomedical nanotechnology, 9(11), 1914-1920 (2013-09-26)
Guided bone regeneration (GBR) is a new method of promoting new bone formation by blocking the proliferation of regenerated connective tissue or providing additional interventions such as direct drug delivery and mechanical support. This in vivo study of bone regeneration
Petra Korlević et al.
BioTechniques, 59(2), 87-93 (2014-01-01)
Although great progress has been made in improving methods for generating DNA sequences from ancient biological samples, many, if not most, samples are still not amenable for analyses due to overwhelming contamination with microbial or modern human DNA. Here we
Minsung Park et al.
Colloids and surfaces. B, Biointerfaces, 130, 222-228 (2015-04-26)
Nanofibrous 2,2,6,6-tetramethylpiperidine-1-oxyl(TEMPO)-oxidized bacterial cellulose (TOBC) was used as a dispersant of hydroxyapatite (HA) nanoparticles in aqueous solution. The surfaces of TOBC nanofibers were negatively charged after the reaction with the TEMPO/NaBr/NaClO system at pH 10 and room temperature. HA nanoparticles
Metallosis and elevated serum levels of tantalum following failed revision hip arthroplasty--a case report.
George C Babis et al.
Acta orthopaedica, 85(6), 677-680 (2014-08-21)
Naomi M de Almeida et al.
Journal of bacteriology, 197(14), 2432-2441 (2015-05-13)
Anaerobic ammonium-oxidizing (anammox) bacteria oxidize ammonium with nitrite as the terminal electron acceptor to form dinitrogen gas in the absence of oxygen. Anammox bacteria have a compartmentalized cell plan with a central membrane-bound "prokaryotic organelle" called the anammoxosome. The anammoxosome
Alberto Nilo et al.
ACS chemical biology, 10(7), 1737-1746 (2015-04-24)
Gram-positive Streptococcus agalactiae or group B Streptococcus (GBS) is a leading cause of invasive infections in pregnant women, newborns, and elderly people. Vaccination of pregnant women represents the best strategy for prevention of neonatal disease, and GBS polysaccharide-based conjugate vaccines
Ioan A Lina et al.
Spine, 39(5), 347-355 (2013-12-25)
A posterolateral rabbit spinal fusion model was used to evaluate the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) and teriparatide (PTH [1-34]) used individually and in combination on spinal fusion outcomes. To test the efficacy of parathyroid hormone on
Paul D Fisher et al.
Journal of biomedical materials research. Part A, 103(7), 2365-2373 (2014-11-27)
In situ forming poly(lactic-co-glycolic acid) (PLGA) implants have not been strongly considered for bone applications because of their poor mechanical properties. Here, in situ forming scaffolds containing hydroxyapatite micro- and nanoparticles were characterized to determine their mechanical properties, injectability, and
J-A Epinette et al.
The bone & joint journal, 95-B(12), 1610-1616 (2013-12-03)
We report a multicentre prospective consecutive study assessing the long-term outcome of the proximally hydroxyapatite (HA)-coated ABG II monobloc femoral component in a series of 1148 hips in 1053 patients with a mean age at surgery of 64.77 years (22
K R Remya et al.
Journal of biomedical nanotechnology, 9(9), 1483-1494 (2013-08-29)
The present work is a comparative evaluation of physical and biological properties of electrospun biodegradable fibrous scaffolds based on polycaprolactone (PCL) and its blend with polycaprolactone-polyethyleneglycol-polycaprolactone (CEC) with and without nanohydroxyapatite (nHAP) particles. The fiber morphology, porosity, surface wettability, and
Liming Jiang et al.
Journal of biomedical nanotechnology, 9(11), 1921-1928 (2013-09-26)
Simvastatin is considered as a stimulator for bone formation. However, the half-life for simvastatin is generally 2 hours, which means, it is difficult to maintain biologically active simvastatin in vivo. To overcome this limitation, we created a system to slowly
Panaghiotis Bazos et al.
The international journal of esthetic dentistry, 9(3), 330-352 (2014-08-16)
A thorough understanding of the spatial distribution pertaining to the histo-anatomic coronal structures and dynamic light interaction of the natural dentition provides the dental team with the ultimate strategic advantage with regards to optical integration of the final restoration. The
Kushagra Saran et al.
Advanced healthcare materials, 4(3), 432-445 (2014-10-10)
During minimally invasive orthopedic surgeries, surgical intervention is required at two stages; to attain hemostasis and subsequently to implant the bone graft or its substitute. There is an apparent need for a material which can simultaneously control bone bleeding and
Bernhard Gasselhuber et al.
Biochemistry, 54(35), 5425-5438 (2015-08-21)
Recently, it was demonstrated that bifunctional catalase-peroxidases (KatGs) are found not only in archaea and bacteria but also in lower eukaryotes. Structural studies and preliminary biochemical data of the secreted KatG from the rice pathogen Magnaporthe grisea (MagKatG2) suggested both
Min-Soo Kim et al.
Journal of periodontal & implant science, 43(1), 18-23 (2013-03-20)
The purpose of this study was to evaluate the osseointegration of calcium phosphate (CaP)-coated implants by ion beam assisted deposition with a lack of primary stability. A total of 20 CaP-coated implants were bilaterally placed in the mandible of five
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