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i1754

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Kimberlee S Mix et al.
Molecular pharmacology, 65(2), 309-318 (2004-01-27)
Matrix metalloproteinases (MMPs) degrade extracellular matrix components, and overexpression of these enzymes contributes to tissue destruction in arthritis. Of particular importance are the collagenases, MMP-1 and MMP-13, which have high activity against the interstitial collagens in cartilage. In this study
Lei He et al.
World journal of gastroenterology, 13(29), 4015-4018 (2007-08-01)
To study the effect of glucose on sodium butyrate-induced proliferation inhibition and apoptosis in HT-29 cell line, and explored its possible mechanisms. HT-29 cells were grown in RPMI-1640 medium supplemented with 10% fetal calf serum, and were allowed to adhere
Yi Zeng et al.
The journal of physical chemistry. A, 115(19), 4995-5004 (2011-04-29)
Computational investigations on the acid-promoted hydrolysis of 2-aryl-4,4-dimethyloxazolin-5-one (AMO) and its seven para- and meta-substituted derivatives (with electron-donating groups R = OH, OCH(3), CH(3) and electron-withdrawing groups R = Cl, m-Cl, CF(3), NO(2)) were presented by the density functional theory
Bert Wouters et al.
Journal of chromatography. A, 1370, 63-69 (2014-12-03)
The gradient-performance limits of capillary ion chromatography have been assessed at maximum system pressure (34.5 MPa) using capillary columns packed with 4.1 μm macroporous anion-exchange particles coated with 65 nm positively-charged nanobeads. In analogy to the van-Deemter curve, the gradient
E Humer et al.
Journal of animal physiology and animal nutrition, 99(4), 788-800 (2014-07-31)
To date, most studies published were carried out on broilers of the same sex, and possible gender-specific effects of phytogenic substances have not been investigated so far. A 3 × 2 factorial study was performed to examine gender-specific effects of a PFA
Baichuan Hu et al.
The journal of physical chemistry. A, 114(1), 355-359 (2009-11-26)
The rate of iodination of acetone has been measured as a function of temperature in the binary solvent isobutyric acid (IBA) + water near the upper consolute point. The reaction mixture was prepared by the addition of acetone, iodine, and
C J L Silwood et al.
Journal of dental research, 81(6), 422-427 (2002-07-05)
We have explored the ability of high-resolution NMR techniques to (1) index salivary biomolecules and (2) provide valuable data regarding intra- and inter-subject variability in the concentrations of a series of components readily determinable by this technique (organic acids and
Timothy Kernan et al.
Biotechnology and bioengineering, 113(1), 189-197 (2015-07-16)
There is growing interest in developing non-photosynthetic routes for the conversion of CO2 to fuels and chemicals. One underexplored approach is the transfer of energy to the metabolism of genetically modified chemolithoautotrophic bacteria. Acidithiobacillus ferrooxidans is an obligate chemolithoautotroph that
Marcos Alexandre Nobre Lemos et al.
Journal of biotechnology, 143(2), 103-110 (2009-07-21)
The cDNA encoding the rabies virus glycoprotein (RVGP) gene was cloned in expression plasmids under the control of the inductive metallothionein promoter. They were designed in order to bear or not a secretion signal (i) and a cDNA coding for
Chen Chen et al.
The journal of adhesive dentistry, 16(2), 169-176 (2014-04-01)
To evaluate the effects of a commercial zirconia primer (Choice or RelyX Unicem) on shear bond strength (SBS) of two different resin composite cements - Choice (a conventional bis-GMA-based resin cement) and RelyX Unicem (self-adhesive resin cement) - to zirconia.
Julia Biermann et al.
Molecular vision, 17, 395-403 (2011-02-12)
Histone deacetylase inhibitors (HDACi) have neuroprotective effects under various neurodegenerative conditions, e.g., after optic nerve crush (ONC). HDACi-mediated protection of central neurons by increased histone acetylation has not previously been demonstrated in rat retinal ganglion cells (RGCs), although epigenetic changes
Daniel Girma Mulat et al.
Talanta, 143, 56-63 (2015-06-17)
In anaerobic digestion of organic matter, several metabolic pathways are involved during the simultaneous production and consumption of short-chain fatty acids (SCFA) in general and acetate in particular. Understanding the role of each pathway requires both the determination of the
Kerry A Lucas et al.
The Journal of biological chemistry, 282(34), 24980-24989 (2007-06-21)
The subcellular sites of branched-chain amino acid metabolism in plants have been controversial, particularly with respect to valine catabolism. Potential enzymes for some steps in the valine catabolic pathway are clearly present in both mitochondria and peroxisomes, but the metabolic
M S P Stevar et al.
Journal of colloid and interface science, 383(1), 184-197 (2012-07-20)
We report optical observations of the dissolution behaviour of glycerol/water, soybean oil/hexane, and isobutyric acid (IBA)/water binary mixtures within horizontal capillary tubes. Tubes with diameters as small as 0.2mm were initially filled with one component of the binary mixture (solute)
Nicoletta Beffagna et al.
Journal of experimental botany, 58(15-16), 4183-4194 (2007-11-28)
In Arabidopsis thaliana cells, fusicoccin (FC) treatment induced an early and marked increase in the extracellular H(2)O(2) level. It also increased the huge hypo-osmotic stress-induced oxidative wave and, in addition, prevented the H(2)O(2) peak drop. These effects were apparently not
Pinal Mistry et al.
Molecular pharmaceutics, 12(9), 3339-3350 (2015-06-14)
The effects of specific drug-polymer interactions (ionic or hydrogen-bonding) on the molecular mobility of model amorphous solid dispersions (ASDs) were investigated. ASDs of ketoconazole (KTZ), a weakly basic drug, with each of poly(acrylic acid) (PAA), poly(2-hydroxyethyl methacrylate) (PHEMA), and polyvinylpyrrolidone
Harry Michael Falk et al.
Bioprocess and biosystems engineering, 38(2), 237-249 (2014-08-22)
An ATR-MIR-FTIR spectrometer was integrated into a laboratory scale anaerobic digestion setup. Automatically, a sludge sample from the digester was transferred to a measurement cell; an IR spectrum was recorded and evaluated by chemometric models to estimate the concentration of
Enbo Xu et al.
Journal of food science, 80(7), C1476-C1489 (2015-06-20)
Enzymatic extrusion, instead of traditional steam cooking, to treat rice is an efficient and alternative pretreatment for Chinese rice wine fermentation. In order to determine the formation of volatiles in enzymatic extrusion-processed rice wine (EE), and to confirm its characteristic
Voravee P Hoven et al.
Journal of colloid and interface science, 314(2), 446-459 (2007-07-31)
A chemically grafted tris(trimethylsiloxy)silyl (tris(TMS)) monolayer on a silicon oxide substrate was used as a template for creating nanoclusters of polymer brushes. Polymer brushes were synthesized by surface-initiated polymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) and tert-butyl methacrylate (t-BMA) via atom transfer
Gamze Bora-Tatar et al.
Bioorganic & medicinal chemistry, 17(14), 5219-5228 (2009-06-13)
In the light of known HDAC inhibitors, 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop the structure-activity relationships of carboxylic acid HDAC inhibitors. HDAC inhibition activities were
Jijian Si et al.
PloS one, 7(9), e43973-e43973 (2012-09-08)
Posttraumatic stress disorder (PTSD) is characterized by acute and chronic changes in the stress response, manifested as conditioned fear memory. Previously formed memories that are susceptible to disruption immediately after retrieval undergo a protein synthesis-dependent process to become persistent, termed
Qiang Liu et al.
Archives of animal nutrition, 62(5), 377-388 (2008-10-24)
The objective of this study was to evaluate the effects of isobutyrate supplementations on rumen fermentation, urinary excretion of purine derivatives and feed digestibility in steers. Eight ruminally cannulated Simmental steers were used in a replicated 4 x 4 Latin
Tomás Rezanka et al.
The Journal of antibiotics, 63(8), 524-529 (2010-07-29)
Precursor-directed biogenetic approach was used to produce a range of nonactin homologues in a 50 l fermentor cultivation of strain Streptomyces griseus 34/249 obtained by UV mutagenesis. The production medium contained sodium propionate, isobutyrate and isovalerate as individual precursors, and
Wei Zhang-Sun et al.
FEBS letters, 589(1), 165-171 (2014-12-06)
The levels of sulfate-reducing bacteria (SRB), including Desulfovibrionaceae, in the gut increase following a fat-enriched diet. Endotoxins from gut microbiota contribute to the inflammation process, leading to metabolic diseases. Thus, we sought to characterize the lipid A structures of Desulfovibrionaceae
A Lopedota et al.
International journal of cosmetic science, 37(4), 438-445 (2015-03-03)
The aim of this study was to prove the capability of β-cyclodextrin (β-CD) to interact with some representative molecules responsible to cause body malodour, such as carboxylic acids, thiols and steroids, present in sweat and body secretions. The association constants
Margaux Cameleyre et al.
Journal of agricultural and food chemistry, 63(44), 9777-9788 (2015-11-04)
This study focused on the impact of five higher alcohols on the perception of fruity aroma in red wines. Various aromatic reconstitutions were prepared, consisting of 13 ethyl esters and acetates and 5 higher alcohols, all at the average concentrations
Doris M Jacobs et al.
Analytical and bioanalytical chemistry, 404(8), 2349-2361 (2012-08-31)
NMR-based metabolite profiling of urine is a fast and reproducible method for detection of numerous metabolites with diverse chemical properties. However, signal overlap in the (1)H NMR profiles of human urine may hamper quantification and identification of metabolites. Therefore, a
Henry Bernard et al.
The Journal of infectious diseases, 211(1), 156-165 (2014-08-21)
A predominantly T-helper type 2 (Th2) immune response is critical in the prognosis of pulmonary Pseudomonas aeruginosa infection. But the mucosal and systemic immune responses can be influenced by the intestinal microbiota. We assessed the effect of microbiota compositional changes
P Madhusudhana Reddy et al.
The journal of physical chemistry. B, 115(42), 12065-12075 (2011-09-21)
We report the influence of variation of molecular weights (MWs = 2, 4, 6, and 9 × 10(5) g mol(-1)) and concentration (C) of a long-chain polymer (polyethylene oxide, PEO) on an upper critical solution temperature (UCST) of isobutyric acid
A Vyalikh et al.
Physical chemistry chemical physics : PCCP, 9(18), 2249-2257 (2007-05-10)
Solid state deuterium NMR has been used to study the molecular motion of d(6)-isobutyric acid (d(6)-iBA) in the pure (unconfined) state and confined in the cylindrical pores of two periodic mesoporous silica materials (MCM-41, pore size 3.3 nm and SBA-15
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