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" no prazo de Papéis
I V Semenova et al.
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury, (2)(2), 23-27 (2012-08-23)
The present clinical immunological study included 90 women of reproductive age presenting with mycoplasma infection of the lower urogenital tract. Low-frequency ultrasonic radiation was shown to successfully correct the disbalance in the system of congenital immunity that manifested itself as
María José González de la Huebra et al.
Journal of pharmaceutical and biomedical analysis, 43(5), 1628-1637 (2007-01-30)
A novel and suitable clean-up method that allows, for the first time, the simultaneous determination of a rather large number of macrolide antibiotics (erythromycin, rosamicin, spiramycin, tylosin, kitasamycin and josamycin in feedingstuffs by high performance liquid chromatography with electrochemical detection
Wen Xie et al.
Se pu = Chinese journal of chromatography, 25(3), 404-407 (2007-08-08)
The macrolides are lipophilic molecules having a central lactone ring bearing 12 to 20 atoms to which several amino and/or neutral sugars are bound. They are broad spectrum antibiotics active against Gram-positive bacteria and mycoplasmas, as well as some Gram-negative
M Ledoux et al.
Annales de dermatologie et de venereologie, 136(1), 37-41 (2009-01-28)
The link between guttate psoriasis and streptococcal infection is acknowledged. This form of psoriasis generally follows pharyngitis, but a small number of cases have been described as being triggered by a streptococcal infection other than in the throat. We report
Adeline Achard et al.
Antimicrobial agents and chemotherapy, 52(8), 2767-2770 (2008-06-04)
Streptococcus uberis UCN60 was resistant to spiramycin (MIC = 8 microg/ml) but susceptible to erythromycin (MIC = 0.06 microg/ml), azithromycin (MIC = 0.12 microg/ml), josamycin (MIC = 0.25 microg/ml), and tylosin (MIC = 0.5 microg/ml). A 2.5-kb HindIII fragment was
Leslie C Dickson
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 967, 203-210 (2014-08-16)
This paper describes an extension and performance characterization of a quantitative confirmatory multi-residue liquid chromatography-tandem mass spectrometric method for residues of macrolide and lincosamide antibiotics, originally validated for application to bovine kidney tissues, to tissues of salmon, shrimp and tilapia.
Zhanhui Wang et al.
Food chemistry, 171, 98-107 (2014-10-14)
Erythromycin is an antibiotic used extensively in veterinary practice worldwide for treatment, prevention and growth promotion. In this work, monoclonal antibodies (Mabs) against erythromycin were produced and used to develop a competitive indirect enzyme-linked immunosorbent assay (ciELISA) for the determination
Sashi Nadanaciva et al.
Journal of biomolecular screening, 15(8), 937-948 (2010-07-14)
Compounds that interfere with the synthesis of either mitochondrial DNA or mtDNA-encoded proteins reduce the levels of 13 proteins essential for oxidative phosphorylation, leading to a decrease in mitochondrial adenosine triphosphate (ATP) production. Toxicity caused by these compounds is seldom
Larissa Van den Bossche et al.
Journal of pharmaceutical and biomedical analysis, 73, 66-76 (2012-02-14)
The European Pharmacopoeia (Ph. Eur.) prescribes a selective and sensitive liquid chromatography/ultraviolet (LC-UV) method for the separation of the 16-membered ring macrolide josamycin and its related compounds. Since josamycin is obtained by fermentation, several closely related substances can be found
Shotaro Nonaka et al.
Journal of medical microbiology, 63(Pt 2), 242-247 (2013-11-08)
We investigated antimicrobial susceptibility and the molecular mechanism involved in conferring high-level macrolide resistance in 47 clinical isolates of Moraxella nonliquefaciens from Japan. Antimicrobial susceptibility was determined using Etest and agar dilution methods. Thirty-two erythromycin-non-susceptible strains were evaluated for the
A A Khrianin et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 52(7-8), 32-36 (2008-11-07)
The present situation with the use of antimicrobial drugs for the management of Chlamydia trachomatis infection during pregnancy in the Russian Federation was evaluated. The efficacy and safety of various macrolides in the treatment of chlamydial infection in practical obstetrics
[Treatment of genital chlamydia infections with wilprafen (josamycin)].
L Damianov
Akusherstvo i ginekologiia, 42 Suppl 2, 35-37 (2003-11-19)
F Daidone et al.
Journal of pharmaceutical and biomedical analysis, 48(2), 347-355 (2008-03-18)
Out of three methods for the analysis of josamycin, the best one was selected and used as starting point for further development. A central composite design was applied to find the most influencing parameters and to optimize the chromatographic conditions
Pushp R Nepal et al.
International journal of pharmaceutics, 341(1-2), 85-90 (2007-05-09)
The aim of this study was to develop floating microspheres with practical applications to fish farming. Each microsphere with a central hollow cavity was prepared using a solvent diffusion and evaporation method with Eudragit E100. Various manufacturing parameters were investigated
I V Khamaganova et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 90-93 (2011-03-31)
To study efficacy of complex therapy of urogenital infections caused by Chlamydia and Mycoplasma using immunomodulator Superlimph. Fifty males and thirty six females ages 22 - 47 years old with chronic urogenital infections--cervicitis and vulvovaginitis (females), prostatitis (males)--were studied. PCR
[A tick bite and lymphadenosis benigna cutis in childhood. Their treatment with josamycin].
I Querol Nasarre et al.
Anales espanoles de pediatria, 39(3), 251-254 (1993-09-01)
Yu-Hong Min et al.
Archives of pharmacal research, 31(3), 377-380 (2008-04-15)
Frequencies of spontaneous mutation from inducible resistance to constitutive resistance were determined for the four clinical isolates of erythromycin-resistant enterococci, including one isolate with ermB gene and three clinical isolates with ermA gene. The rate of ermB mutation was higher
Martin Lovmar et al.
Biochimie, 91(8), 989-995 (2009-05-26)
Macrolide antibiotics block the entrance of nascent peptides to the peptide exit tunnel of the large ribosomal subunit. Expression of specific cis-acting peptides confers low-level macrolide-resistance. We show that, in the case of josamycin, peptide expression does not eject josamycin
Piotr Przybylski et al.
Magnetic resonance in chemistry : MRC, 48(4), 286-296 (2010-02-27)
Four new hydroxy-aminoalkyl derivatives of alpha,beta-unsaturated macrolide-josamycin (2-5) have been synthesised and their structures have been studied by means of (1)H and (13)C NMR and FT-IR methods. Complete assignment of resonances in the (1)H and (13)C NMR spectra has been
Iu N Perlamutrov et al.
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury, (3)(3), 45-51 (2013-07-04)
The prevalence of cytomegalovirus infection (CMVI) dictates the necessity of its in-depth investigation in the patients presenting with the signs of chronic inflammatory diseases of sexual organs. The objective of the present study was to estimate the effectiveness of combined
Takeshi Shimizu et al.
Mediators of inflammation, 2012, 265714-265714 (2012-05-12)
To examine the in vivo effects of the 15-member macrolide, azithromycin (AZM), on mucus hypersecretion, we induced hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium by intranasal instillation of ovalbumin (OVA) in OVA-sensitized rats, or by intranasal
M Weidlich et al.
Letters in applied microbiology, 46(2), 155-159 (2007-11-22)
Evaluation of the activity profiles of standard prokaryotic translation inhibitors with different physicochemical properties under whole-cell and cell-free conditions. The minimal inhibitory concentration values (cell-free/whole-cell microg ml(-1)) for three aminoglycosides (neomycin, 0.01/6.92; paromomycin, 0.7/1.96; streptomycin 1.45/1.57), three macrolides (erythromycin, 1.53/56.9;
Xue-Mei Ou et al.
Respirology (Carlton, Vic.), 13(1), 63-72 (2008-01-17)
To examine the effect of a 14-membered ring macrolide on airway mucus hypersecretion in rats treated with LPS. Mucus hypersecretion in rat airways was induced by intratracheal instillation of LPS. Rats treated with or without LPS were administered roxithromycin (1-10
Outcome of very preterm infants with Mycoplasma/Ureaplasma airway colonization treated with josamycine.
H See et al.
Acta paediatrica (Oslo, Norway : 1992), 99(4), 625-626 (2010-01-09)
Giuseppe Alessio Messano et al.
Igiene e sanita pubblica, 67(6), 697-706 (2012-04-18)
Antibiotic resistance is an emerging public health problem especially due to the continuous use of antibiotics that selects more aggressive and resistant species. In the present study the authors determined the antibiotic sensitivity of 128 Mycoplasma hominis strains obtained from
Fragmentation pathways of new aza derivatives of 16-membered macrolide antibiotic--analog of Josamycin investigated by ESI and FAB mass spectrometric methods.
Piotr Przybylski et al.
Journal of mass spectrometry : JMS, 44(9), 1395-1401 (2009-07-02)
Biyang Deng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 859(1), 125-130 (2007-10-12)
A novel determination method for josamycin (JOS) based on capillary electrophoresis-electrochemiluminescence detection has been described. In this study, platinum disk electrode (300 microm in diameter) was used as a working electrode and the conditions affecting separation and detection were investigated
U Colombo et al.
Minerva ginecologica, 50(11), 491-497 (1999-01-12)
The macrolides are among the most effective antibiotics against infections due to Chlamydia and Mycoplasma. The drug in such cases must have marked antibacterial activity, good oral bioavailability, and high intracellular diffusion--indispensable for instance with Chlamydia infection. Rokitamycin, a macrolide
Maki Kanda et al.
Journal of AOAC International, 98(1), 230-247 (2015-04-11)
Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using a validated LC-MS/MS method. There were two key points in sample preparation. First, extraction was
I V Andreeva et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 57(5-6), 32-40 (2012-11-20)
The aim of the study was to estimate the diagnostic and treatment patterns in the management of acute nongonococcal urethritis (NGU) in males in some cities of Russia. Retrospective cross-sectional study was conducted in 2009 in 5 centers of 4
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