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Superhydrophobic surfaces allow probing of exosome self organization using X-ray scattering.

Nanoscale (2013-02-22)
Angelo Accardo, Luca Tirinato, Davide Altamura, Teresa Sibillano, Cinzia Giannini, Christian Riekel, Enzo Di Fabrizio
ABSTRACT

Drops of exosome dispersions from healthy epithelial colon cell line and colorectal cancer cells were dried on a superhydrophobic PMMA substrate. The residues were studied by small- and wide-angle X-ray scattering using both a synchrotron radiation micrometric beam and a high-flux table-top X-ray source. Structural differences between healthy and cancerous cells were detected in the lamellar lattices of the exosome macro-aggregates.

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