• Início
  • Resultados da busca
  • Hydroxyapatite and collagen combination-coated dental implants display better bone formation in the peri-implant area than the same combination plus bone morphogenetic protein-2-coated implants, hydroxyapatite only coated implants, and uncoated implants.

Hydroxyapatite and collagen combination-coated dental implants display better bone formation in the peri-implant area than the same combination plus bone morphogenetic protein-2-coated implants, hydroxyapatite only coated implants, and uncoated implants.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (2013-12-18)
Sang-Woon Lee, Byung-Dong Hahn, Tae Yeon Kang, Myung-Jin Lee, Je-Yong Choi, Min-Keun Kim, Seong-Gon Kim
RESUMO

The objective of this study was to compare peri-implant bone formation among uncoated (UC), hydroxyapatite (HA), collagen plus HA (CH), and collagen, HA, plus bone morphogenetic protein-2 (BMP-2) implant groups. Implants in the UC group had acid-etched surfaces. The surface coating was applied using the aerosol deposition method. The coated surfaces were examined by scanning electron microscopy, x-ray diffraction (XRD), and Fourier-transformed infrared absorption analysis. Subsequently, 6 implants from each group (total, 24 implants) were installed in the tibias of rabbits. The animals were sacrificed at 6 weeks after implant installation. Peri-implant bone formation and bone-to-implant contact (BIC) were measured in histologic sections. Significant differences among groups were evaluated using analysis of variance. Based on the measured XRD patterns, there was a characteristic HA phase (International Centre for Diffraction Data [ICDD], 086-0740) coated on the titanium (ICDD, 089-3725). Subsequent coating processes for collagen and BMP-2 did not display additional diffraction peaks, but maintained the diffraction patterns of the HA-coated titanium. The presence of collagen was verified by infrared absorption analysis. When comparing these modifications with UC surfaces, only the CH coating displayed significantly greater peri-implant bone formation and BIC (P = .003 and P < .001, respectively). Adding BMP-2 to the implant surface did not produce any advantage compared with the CH coating. In this study, the CH group displayed significantly greater new bone formation and BIC than the other groups. There was no significant difference among the other groups.

MATERIAIS
Número do produto
Marca
Descrição do produto

Sigma-Aldrich
Titanium, foil, thickness 0.127 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.25 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium, powder, <45 μm avg. part. size, 99.98% trace metals basis
Sigma-Aldrich
Hydroxyapatite, puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)
Sigma-Aldrich
Titanium, powder, −100 mesh, 99.7% trace metals basis
Sigma-Aldrich
Hydroxyapatite, purum p.a., ≥90% (as Ca3(PO4)2, KT)
Sigma-Aldrich
Hydroxyapatite, Type I, buffered aqueous suspension
Sigma-Aldrich
Titanium, foil, thickness 0.025 mm, 99.98% trace metals basis
Sigma-Aldrich
Titanium, wire, diam. 0.25 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium, sponge, 3-19 mm, 99.5% trace metals basis
Sigma-Aldrich
Titanium, nanoparticles, dispersion, <100 nm particle size, in mineral oil, 98.5% trace metals basis
Sigma-Aldrich
Titanium, sputtering target, diam. × thickness 2.00 in. × 0.25 in., 99.995% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.5 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 2.0 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium, wire, diam. 0.81 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.25 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, crystalline, 5-10 mm, ≥99.99% trace metals basis (purity exclusive of Na and K content)
Sigma-Aldrich
Titanium, evaporation slug, diam. × L 6.3 mm × 6.3 mm, ≥99.99% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.127 mm, ≥99.99% trace metals basis
Sigma-Aldrich
Titanium, wire, diam. 1.0 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, wire, diam. 0.5 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, wire, diam. 2.0 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, wire, diam. 0.127 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, sputtering target, diam. × thickness 3.00 in. × 0.125 in., 99.995% trace metals basis
Sigma-Aldrich
Titanium, rod, diam. 6.35 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.1 mm, 99.99% trace metals basis
Titanium, IRMM®, certified reference material, 0.5 mm wire
Titanium, IRMM®, certified reference material, 0.1 mm foil
Titanium, IRMM®, certified reference material, 0.5 mm foil