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Bioavailability and biological activity of L-ascorbic acid 2-O-alpha-glucoside.

Journal of nutritional science and vitaminology (1992-01-01)
I Yamamoto, N Muto
ABSTRACT

AA-2G is a new stable derivative of AsA which is efficiently synthesized by regioselective transglucosylation with alpha-glucosidase and CGTase. AA-2G serves as a vitamin C supplement in experimental animals. AA-2G is easily hydrolyzed in vivo by alpha-glucosidase and also synthesized as a metabolite under some specified conditions. AA-2G stimulates collagen synthesis in cultured fibroblasts and enhances antibody production in cultured splenocytes. AA-2G which has no cytotoxicity is a promising AsA derivative for medical and nutritional uses.

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