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440140

Sigma-Aldrich

(3-Aminopropyl)triethoxysilane

99%

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Synonym(s):
3-Triethoxysilylpropylamine, APTES, APTS
Linear Formula:
H2N(CH2)3Si(OC2H5)3
CAS Number:
Molecular Weight:
221.37
Beilstein:
1754988
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

Assay

99%

form

liquid

bp

217 °C/760 mmHg (lit.)

density

0.946 g/mL at 25 °C (lit.)

SMILES string

CCO[Si](CCCN)(OCC)OCC

InChI

1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3

InChI key

WYTZZXDRDKSJID-UHFFFAOYSA-N

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1 of 4

This Item
A3648741442706493
vibrant-m

440140

(3-Aminopropyl)triethoxysilane

vibrant-m

A3648

(3-Aminopropyl)triethoxysilane

vibrant-m

741442

(3-Aminopropyl)triethoxysilane

vibrant-m

706493

(3-Aminopropyl)triethoxysilane

form

liquid

form

liquid

form

liquid

form

liquid

density

0.946 g/mL at 25 °C (lit.)

density

0.946 g/mL at 25 °C (lit.)

density

0.929 g/mL at 25 °C, 0.946 g/mL at 25 °C (lit.)

density

0.946 g/mL at 25 °C (lit.)

bp

217 °C/760 mmHg (lit.)

bp

217 °C/760 mmHg (lit.)

bp

217 °C/760 mmHg (lit.)

bp

217 °C/760 mmHg (lit.)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

General description

(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.

Application

Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures. Recently (3-Aminopropyl)triethoxysilane has been used to prepare dye-doped silica nanoparticles with minimal aggregation and minimal nonspecific binding with biomolecules.
Self-assembled monolayer (SAM) of APTES can be used to improve the adhesion of graphene flakes and SiO2 to enable better contact with the metal electrodes. These electrodes may be used as electro-responsive tools for bio-sensing applications. It can be used to functionalize silane diazirine for fiber optic biosensor application. Hollow microcarriers (HMCs) can be surface modified with APTES which may be used for regenerative medicines and recombinant cells in biopharmaceutical industries.
Used in a preparation of a series of tenary composite films of polyimide/SiO/polydiphenylsiloxane with good optical transparency.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

199.4 °F - closed cup

Flash Point(C)

93 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Polymer International, 55, 1277-1277 (2006)
Functionalisation of Detonation Nanodiamond for Monodispersed, Soluble DNA-Nanodiamond Conjugates Using Mixed Silane Bead-Assisted Sonication Disintegration.
Edgington, et al.
Scientific Reports, 8(1), 728-728 (2018)
Hollow microcarriers for large-scale expansion of anchorage-dependent cells in a stirred bioreactor.
YekrangSafakar, et al.
Biotechnology and Bioengineering, 115(7), 1717-1728 (2018)
Effect of divalent versus monovalent cations on the MS2 retention capacity of amino-functionalized ceramic filters.
Bartels J, et al.
Physical Chemistry Chemical Physics, 20(16), 11215-11223 (2018)
Platinum nanoparticles homogenously decorating multilayered reduced graphene oxide for electrical nanobiosensor applications.
Proa-Coronado, et al.
Thin Solid Films, 658(1), 54-60 (2018)

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