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605166

L-Glutamine-13C5

98 atom % 13C, 95% (CP)

Synonym(s):

(S)-2,5-Diamino-5-oxopentanoic acid-13C5, L-Glutamic acid 5-amide-13C5, L-Glutamine-ul-13C, 13C Labeled glutamine

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About This Item

Linear Formula:
H2N13CO(13CH2)213CH(NH2)13CO2H
CAS Number:
184161-19-1
Molecular Weight:
151.11
NACRES:
NA.12
PubChem Substance ID:
24881903
UNSPSC Code:
12352209
MDL number:
MFCD00144603
Isotopic purity:
98 atom % 13C
Assay:
95% (CP)
Mass shift:
M+5
Form:
solid

Key Documents

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InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i1+1,2+1,3+1,4+1,5+1

SMILES string

[H][13C@](N)([13CH2][13CH2][13C](N)=O)[13C](O)=O

InChI key

ZDXPYRJPNDTMRX-WIAREEORSA-N

isotopic purity

98 atom % 13C

assay

95% (CP)

form

solid

optical activity

[α]25/D +33.0°, c = 2 in 5 M HCl

mp

185 °C (dec.) (lit.)

mass shift

M+5

storage temp.

room temp

Quality Level

200

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This Item
604860607983635081
L-Glutamine-13C5 98 atom % 13C, 95% (CP)

Sigma-Aldrich

605166

L-Glutamine-13C5

L-Glutamic acid-13C5 98 atom % 13C, 95% (CP)

Sigma-Aldrich

604860

L-Glutamic acid-13C5

L-Glutamine-13C5,15N2 98 atom % 13C, 98 atom % 15N

Sigma-Aldrich

607983

L-Glutamine-13C5,15N2

L-Glutamine-13C5,15N2,d10 98 atom % 13C, 98 atom % 15N, 96 atom % D, 95% (CP)

Sigma-Aldrich

635081

L-Glutamine-13C5,15N2,d10

mass shift

M+5

mass shift

M+5

mass shift

M+7

mass shift

M+17

assay

95% (CP)

assay

95% (CP)

assay

95% (CP)

assay

95% (CP)

isotopic purity

98 atom % 13C

isotopic purity

98 atom % 13C

isotopic purity

98 atom % 13C, 98 atom % 15N

isotopic purity

98 atom % 13C, 98 atom % 15N, 96 atom % D

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

solid

form

solid

form

solid

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

-

Application

L-Glutamine-13C5 has been used for gas chromatography-mass spectrometry (GC-MS) of RAW264.7 cells.[1] It has also been used for metabolomics analysis in p53Mut-parental mesenchymal stem cells (MSCs) or p53Mut-MSC-tumor lines.[2]

General description

L-Glutamine plays an important role in nucleotide synthesis. It functions as a critical fuel for lymphocytes and gut epithelial cells. L-Glutamine is essential in the endogenous synthesis of glutathione.[3] It is an essential amino acid, which is useful in stressful conditions. L-Glutamine is involved in protein synthesis, wound healing, regulating acid-base balance, cellular differentiation, acts as an energy source and modulates the immune system.[4]

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MBBD6010
MBBD5191
MBBD4244
MBBD1582
MBBC9711

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Mutant p53-dependent mitochondrial metabolic alterations in a mesenchymal stem cell-based model of progressive malignancy
Lonetto G, et al.
Cell Death and Differentiation, 1-1 (2018)
Kyung-Hee Kim et al.
Oncotarget, 8(68), 112598-112609 (2018-01-20)
We searched for metabolic biomarkers that may predict the prognosis of patients with intrahepatic cholangiocarcinoma (IHCC). To this end, a total of 237 serum samples were obtained from IHCC patients (
Surgical Critical Care, An Issue of Surgical Clinics - E-Book (2012)
TiO2 nanoparticles cause mitochondrial dysfunction, activate inflammatory responses, and attenuate phagocytosis in macrophages: A proteomic and metabolomic insight
Chen Q, et al.
Redox Biology, 15, 266-276 (2018)
Leonie Drews et al.
Disease models & mechanisms, 13(10) (2020-09-13)
Astrocyte dysfunction is a primary factor in hepatic encephalopathy (HE) impairing neuronal activity under hyperammonemia. In particular, the early events causing ammonia-induced toxicity to astrocytes are not well understood. Using established cellular HE models, we show that mitochondria rapidly undergo
View All Related Papers

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