KITALYSIS-BOR

KitAlysis^™ High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2

• NACRES: NA.21
• UNSPSC Code: 12161600

Properties

• product line: KitAlysis^™
• reaction suitability: reagent type: catalyst; core: palladium; reaction type: Miyaura Borylation Reaction
• functional group: phosphine

Description

General description

The KitAlysis High-Throughput Miyaura Borylation Reaction Screening Kit enables chemists to quickly and efficiently screen reaction conditions for Pd catalyzed Miyaura borylation reactions. Quick identification of optimal conditions allows faster scale-up of the desired synthetic transformation. All required chemicals come pre-weighed for ease of use. A step-by-step user guide and experimental excel sheets are available for download to facilitate the process.

Application

Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.
Step-by-Step Guide for Miyaura Borylation Reaction Screening Kit
Downloadable Experiment excel sheets

Each kit contains 2 customizable screening sets that include the following components:

• 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
• 4 x 4 mL reaction vials with pre-weighed KOAc
• Bis(pinacolato)diboron (473294), tetrahydroxydiboron (754242), and pinacol (221171)
• 1 (2 mL) ampule each of toluene, THF, n-butanol, DMA, MeOH, MeCN, ethylene glycol and DIPEA.
• 1 NEW KitAlysis 24-Well Reaction Block Replacement Film.
• 4 stir bars for substrate stock solution vials.
• 1 internal standard.

Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

• Designed and tested by synthetic chemists.
• Easily run 24-microscale reactions in parallel.
• 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
• Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Kit Components Also Available Separately

• 764175

  P(Cy₃) Pd G3, 97%

  SDS
• 791733

  Potassium acetate, anhydrous, free-flowing, Redi-Dri^™, ACS reagent, ≥99.0%

  SDS
• 804274

  XPhos Pd G4, 95%

  SDS
• 804282

  SPhos Pd G4

  SDS
• 804290

  RuPhos Pd G4

  SDS
• 804975

  DTBPF-Pd-G3

  SDS
• 900349

  cataCXium A Pd G4

  SDS

See All (21)

Safety Information

• pictograms: GHS02,GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• target_organs: Central nervous system, Eyes,Central nervous system, Kidney, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• flash_point_f: 1.4 °F
• flash_point_c: -17 °C
• wgk: WGK 3
• hcodes: H225,H301 + H311 + H331,H304,H315,H318,H335,H336,H351,H360D,H370,H373,H410
• pcodes: P210 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P331
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT RE 2 Oral - STOT SE 1 - STOT SE 3