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1.14894

Fractogel® EMD SE Hicap (M)

strong cation exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)

Synonym(s):

Fractogel® EMD SE Hicap (M)


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10 ML

$154.00

100 ML

$1,230.00

500 ML

$4,350.00

5 L

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$154.00


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About This Item

UNSPSC Code:
41115711

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ligand

(Sulfoethyl)

Quality Level

product line

Fractogel®

form

resin

specific analyte(s)

MAbs

parameter

220 cm/hr flow rate, 8 bar max. pressure

matrix active group

methacrylate

mean particle size

40-90 μm

capacity

160 mg binding capacity (lysozyme/ml of resin)

transition temp

flash point 35 °C (calculated)

application(s)

recombinant protein
vaccine development

separation technique

cation exchange, strong cation exchange

storage temp.

2-30°C

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1 of 4

This Item
1.168841.168821.16890
ligand

(Sulfoethyl)

ligand

diethylaminoethyl

ligand

(Sulfoisobutyl)

ligand

(Sulfoisobutyl)

form

resin

form

resin

form

resin

form

resin

separation technique

cation exchange, strong cation exchange

separation technique

weak anion exchange

separation technique

cation exchange, strong cation exchange

separation technique

strong cation exchange

sterility

sterile (Caustic Stable)

sterility

sterile (Caustic Stable)

sterility

sterile (Caustic Stable)

sterility

sterile (Caustic Stable)

specific analyte(s)

MAbs

specific analyte(s)

-

specific analyte(s)

MAbs

specific analyte(s)

-

matrix active group

methacrylate

matrix active group

methacrylate

matrix active group

methacrylate

matrix active group

methacrylate

General description

Strong cation exchange Fractogel® resin featuring the tentacle technology, for purification of basic and neutral proteins (e.g. antibodies) and peptides

Features and Benefits

Fractogel® EMD SE Hicap (M) features include:

  • Tentacle technology provides high yield, selectivity, and focused elution
  • High loading capacity combined with high purity at lower elution volumes
  • Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution

Packaging

  • 1.14894.0100: Fractogel® EMD SE Hicap (M) Resin 100ml
  • 1.14894.0010: Fractogel® EMD SE Hicap (M) Resin 10ml
  • 1.14894.0500: Fractogel® EMD SE Hicap (M) Resin 500ml
  • 1.14894.5000: Fractogel® EMD SE Hicap (M) Resin 5L

Plastic bottle

Analysis Note

Appearance: Milky turbid suspension,free from impurities(foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.08 %
Cerium: ≤ 20 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 120 - 160 mg/ml
Functional test (b:a): ≤ 0.20
Functional test: Separation of chymotrypsinogen A and lysozyme

Legal Information

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids


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