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234567M

Sigma-Aldrich

Concanavalin A, Canavalia ensiformis

Concanavalin A, Canavalia ensiformis, CAS 11028-71-0, is a carbohydrate-binding protein that agglutinates various animal cells. Restores the growth pattern of tumor cells to that of normal cells.

Synonym(s):

Concanavalin A, Canavalia ensiformis, Con A, Jack Bean Hemagglutinin

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250 MG
$307.00
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$1,010.00

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250 MG
$307.00
1 G
$1,010.00

About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.42

$307.00


In StockDetails


Quality Level

description

Merck USA index - 14, 2495

form

lyophilized

potency

≤20 μg/mL lectin agglutination activity (as determined from serial dilutions of a 1 mg/mL solution)

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

pI 

4.5 - 5.5

storage temp.

2-8°C

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This Item
C2272C2010C5275
form

lyophilized

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage condition

OK to freeze

storage condition

-

storage condition

-

storage condition

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

potency

≤20 μg/mL lectin agglutination activity (as determined from serial dilutions of a 1 mg/mL solution)

potency

-

potency

<64 μg per mL agglutination activity

potency

-

description

Merck USA index - 14, 2495

description

-

description

-

description

-

General description

Carbohydrate-binding protein that agglutinates various animal cells. Also known to restore the growth pattern of tumor cells to that of normal cells. T lymphocyte activator. Has binding sites for metal ions, α-D-mannose, and α-D-glucose. Has a pI of 4.5-5.5.

Warning

Toxicity: Harmful (C)

Preparation Note

To dissolve, add Con A slowly to a solution of 10 mM HEPES buffered saline, 100 µM CaCl₂, pH 8.5. Allow the lectin to dissolve without agitation.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) or add 0.08% NaN₃ and refrigerate (4°C). Stock solutions are stable for up to 6 months at -20°C or for up to 3 months at 4°C.

Analysis Note

The agglutination activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25°C; requires type A human blood.

Other Notes

Gantner, F., et al. 1995. Hepatology 21, 190.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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