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1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem

A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.

Synonym(s):

1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem, DNJ, HCl

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About This Item

Empirical Formula (Hill Notation):
C6H13NO4 · xHCl
CAS Number:
Molecular Weight:
163.17 (free base basis)
MDL number:
UNSPSC Code:
12352200

Quality Level

Assay

≥98% (TLC)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

solubility

water: 100 mM

shipped in

ambient

storage temp.

2-8°C

General description

A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.
Specific glucosidase inhibitor, including trimming glucosidases I and II, that sequentially removes the three glucose residues from precursor Glc3Man9GlcNAc2 in N-linked glycan biosynthesis.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Glucosidase 1, glucosidase 2
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Suh, K., et al. 1992. J. Biol. Chem. 267, 21671.
Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta825, 95.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Customers Also Viewed

K Suh et al.
The Journal of biological chemistry, 267(30), 21671-21677 (1992-10-25)
The role of glucosylated oligosaccharides in the biogenesis of the glycoprotein (G protein) of vesicular stomatitis virus was studied in PhaR2.7, a mouse lymphoma cell line deficient in glucosidase II activity. As expected, the great majority of cell-associated G protein
Inhibitors of oligosaccharide processing.
U Fuhrmann et al.
Biochimica et biophysica acta, 825(2), 95-110 (1985-06-24)

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