497985
Ornithine Decarboxylase Inhibitor, POB - Calbiochem
Synonym(s):
N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB, Ornithine Decarboxylase Inhibitor, POB - Calbiochem
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10 MG
$162.00
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10 MG
$162.00
About This Item
Linear Formula:
C19H31N3O6
UNSPSC Code:
12352200
NACRES:
NA.28
form
(White to off-white solid)
Quality Level
storage condition
OK to freeze
solubility
soluble (H2O (1 mg/ml))
storage temp.
2-8°C
General description
A cell-permeable pyridoxyl-ornithine compound that acts as an effective analog of the transition state coenzyme-substrate adduct during orthithine decarboxylase- (ODC) catalyzed conversion of L-orthithine to Pultrescine. POB is typically 5- to 10-fold more potent than DFMO (Cat. No. 288500) in inhibiting intracellular ODC activity and tumor cell growth in cultures, while exhibiting little effect against the growth of nontumorigenic human aortic smooth muscle cells.
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