MilliporeSigma
All Photos(1)

GF319

Sigma-Aldrich

BMP-2, Human Recombinant
Animal Free

Synonym(s):
BMP2, BMP 2A, BMP 2, BMP2A, bone morphogenetic protein 2
eCl@ss:
32160405

impurities

<0.1 μg/mg protein endotoxin (<1 EU/μg)

Quality Level

UniProt accession no.

shipped in

dry ice

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GF166GF302GF342
impurities

<0.1 μg/mg protein endotoxin (<1 EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1 EU/μg)

UniProt accession no.

P12643

UniProt accession no.

P12643

UniProt accession no.

P12644

UniProt accession no.

P15018

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

General description

BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues including lung, liver, spleen, prostate, ovary, and small intestine. Recombinant human BMP-2 is a 26.0 kDa homodimeric disulfide-linked protein consisting of two identical 115 amino acid chains.

Quality

Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 2


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