MABX1901

Anti-human IgG (1mg) KC

from mouse

• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• antibody form: purified antibody
• antibody product type: secondary antibodies
• clone: monoclonal
• species reactivity: human
• technique(s): ELISA: suitable; immunodiffusion: suitable
• isotype: IgG2b

Description

General description

Secondary antibody specific for Human Immunoglobulin G
Immunoglobulin G (IgG), an immunoglobulin isotype, is the most abundant protein in human serum and constitutes 10-20% of plasma protein. It is composed of glycoproteins comprising 82-96% of proteins and 4-18% of carbohydrates. IgG is further classified into IgG1, IgG2, IgG3, and IgG4 subclasses. IgG consists of four polypeptide chains, with two heavy chains (γ chains) and two light chains (κ or λ chains), which are linked by inter-chain disulfide bonds. It is secreted by B lymphocytes and found in extracellular fluids and blood.

Specificity

Specific for Human IgG. No cross reactivity with human IgA, IgD, IgE or IgE.

Immunogen

corresponding to Human Serum IgG.

Application

Detect Human Serum IgG using this mouse monoclonal Anti-human IgG (1mg) KC, Cat. No. MABX1901-1KC, validated for use in Lateral Flow Assay and ELISA.

Biochem/physiol Actions

Immunoglobulin G (IgG) primarily contributes to the humoral immune response by neutralizing pathogens such as bacteria, viruses, and protect cells from their toxic substances. IgG is the only isotype transferred to the fetus across the placenta and is vital for immune response of the neonate. Alterations in IgG fragment crystallizable (Fc)-glycosylation are associated with various diseases including rheumatoid arthritis and tuberculosis.

Quality

Tested

Physical form

Format: Purified

Other Notes

Concentration: Please refer to lot specific datasheet.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable