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$1,540.00
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About This Item
$1,540.00
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biological source
human
Quality Level
packaging
vial of >1X10⁶ cells
manufacturer/tradename
Millipore
growth mode
N/A
technique(s)
cell culture | mammalian: suitable
shipped in
liquid nitrogen
storage temp.
−196°C
Application
- Each vial contains > 1X106 viable cells.
- Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
- Cells are verified to be of human origin and negative for inter-species contamination from mouse, rat, chinese hamster, Golden Syrian hamster, and Non-human Primate (NHP) as assessed by a Contamination Clear panel by Charles River Animal Diagnostic Services
- Cells are negative for mycoplasma contamination.
The SK-MEL-37 amelanotic cutaneous melanoma cell line is a well-established model for human melanoma, widely utilized in investigations into the mutational landscape of melanoma and the enhanced antigen expression that occurs concomitantly with melanoma progression. SK-MEL-37 expresses the melanoma-associated antigens MAGE-A1, tyrosinase, and p97, and cell surface antigens essential for metastasis such as CD71 and CD146.3 SK-MEL-37 is valuable and highly characterized cell system for transformation of melanocytes into melanoma and identification of therapeutic targets for this disease.
Source
SK-MEL-37 was established from a metastatic lymph node of a 65-year old male patient with malignant melanoma of rectal tumor origin.4
References
1. CA Cancer J Clin 2019, 69(1): 7-34.
2. Cancers (Basel) 2020, 12(9): 2362.
3. J Cancer 2013, 45(5): 371-382.
4. J Exp Med 1976, 144(4): 873
Features and Benefits
Storage and Stability
Other Notes
Disclaimer
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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