W2660

1,2-Distearoyl-sn-glycero-3-phosphocholine

DSPC, GMP, powder

• Synonym(s): PC(18:0/18:0), 18PC, 3-sn-Phosphatidylcholine, 1,2-distearoyl, 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, DSPC, PC, 18:0 PC, Phospholipid, L-β,γ-Distearoyl-α-lecithin, L-α-Phosphatidylcholine, distearoyl
• Empirical Formula (Hill Notation): C₄₄H₈₈NO₈P
• CAS Number: 816-94-4
• Molecular Weight: 790.15
• Beilstein: 3923978
• MDL number: MFCD00036905

Properties

• Quality Level: 500
• biological source: synthetic
• grade: GMP
• form: powder
• packaging: pkg of 1 g; pkg of 10 g; pkg of 100 g; pkg of 1000 g
• transition temp: transition temp 55 °C
• application(s): pharmaceutical
• storage temp.: −20°C (−15°C to −25°C)
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
• InChI key: NRJAVPSFFCBXDT-HUESYALOSA-N

Description

General description

A GMP-scalable process which yields a high-quality lipid is essential to lipidic drug product development and manufacturing. We are highly specialized in synthesizing top-quality GMP lipids for pharmaceutical applications and gene therapy, focusing on tailored manufacturing to meet your specific needs. We also offer an off-the-shelf catalog with optimized stability, solubility, and handling characteristics.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Non-pyrogenic, well-defined liposomes, loaded with a molecule of choice, are formed by a single hydration step.

Application

DSPC is used as a structural lipid in the preparation of lipid-based systems like liposomes and lipid nanoparticles (LNPs).
This product is GMP grade and suitable for divers formulation applications ranging from lipid nanoparticle and liposomes to microbubbles for ultrasound contrast agents.

Packaging

Amber glass screw cap bottle, bubble wrap outer bag

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable